gene expression

[ Embargoed PhD thesis; abstract only. ] Abstract Background: Myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS) is a disabling multisystem complex disorder with no known etiology or approved treatment. Our studies aimed to assess the link between ME/CFS and autoimmune disease (AID)...

Free fulltext: https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-024-05117-7 Research Open access Published: 26 March 2024 Bulk RNA sequencing for analysis of post COVID-19 condition in adolescents and young adults Silke Lauren Sommen, Zhi Zhao, Sunniva Segtnan, Tonje...

A 50-gene high-risk profile predictive of COVID-19 and Idiopathic Pulmonary Fibrosis mortality originates from a molecular imbalance in monocyte and T-cell subsets that reverses in survivors with post-COVID-19 Interstitial Lung Disease Bochra Tourki; Minxue Jia; Theodoros Karampitsakos; Iset M...

Genomic communication via circulating extracellular vesicles and long-term health consequences of COVID-19 Nair, Soumyalekshmi; Nova-Lamperti, Estefania; Labarca, Gonzalo; Kulasinghe, Arutha; Short, Kirsty R.; Carrión, Flavio; Salomon, Carlos COVID-19 continues to affect an unprecedented number...

Exploring the mechanisms of long COVID: Insights from computational analysis of SARS-CoV-2 gene expression and symptom associations Abstract Long coronavirus disease (COVID) has emerged as a global health issue, affecting a substantial number of people worldwide. However, the underlying...

Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic, complex multi-organ illness characterized by unexplained debilitating fatigue and post-exertional malaise (PEM), which is defined as a worsening of symptoms following even minor physical or mental exertion. Our...

Diurnal transcriptome landscape of a multi-tissue response to time-restricted feeding in mammals Shaunak Deota, Terry Lin, Amandine Chaix, April Williams, Hiep Le, Hugo Calligaro, Ramesh Ramasamy, Ling Huang, Satchidananda Panda Time-restricted feeding (TRF) is an emerging behavioral nutrition...

Abstract Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating condition that can lead to severe impairment of physical, psychological, cognitive, social, and occupational functions. The cause of ME/CFS remains incompletely understood. There is no clinical...

Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is a multisystem disease, the pathogenesis of which remains undetermined. We set out to determine the precise abnormalities of gene expression in the blood of patients with CFS/ME. We analyzed gene expression in peripheral blood from 25...

https://medicalxpress.com/news/2022-04-scientists-uncover-covid-pain.html

Winter is always worse for my daughter- this is a study looking at gene expression and seasons as the seasonal effect is well known in both mainstream and psychiatric conditions. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449160/?s=09

Apparently most of the population have variants or absence of the CYP2C19 gene. But how do I figure out from the raw genetic data (rs17878459 etc numbers, and alleles) which variants I do or don't have? I'm working from SNPedia but usually it's just a case of checking the rs number, and...

I found it interesting that the affected genes in the study (ALAD and p16) are involved in red blood cell development and some cancers. Lead poisoning could reduce gene expression in humans Scientists have unveiled a correlation between high blood lead levels in children and methylation of...

Source: Clinical Therapeutics Preprint Date: March 6, 2019 URL: https://www.sciencedirect.com/science/article/abs/pii/S0149291819300475 Treatment avenues in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A split-gender pharmacogenomic study of gene-expression modules...

Provisionally accepted https://www.frontiersin.org/articles/10.3389/fped.2019.00059/full full paper here: http://sci-hub.tw/https://www.frontiersin.org/articles/10.3389/fped.2019.00059/full I haven't read it all but not sure if I've posted it in the correct forum?: "EBV reactivation is a...

Gene activation precedes DNA demethylation in response to infection in human dendritic cells Alain Pacis, Florence Mailhot-Leonard, Ludovic Tailleux, Haley E Randolph, Vania Yotova, Anne Dumaine, Jean-Christophe Grenier, Luis B Barreiro doi: https://doi.org/10.1101/358531 This article is a...