Central origin of fatigability in Myalgic encephalomyelitis/chronic fatigue syndrome revealed by multimodal neuroimaging
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating chronic disease characterized by physical and mental fatigue, post-exertional malaise, muscle...
Repeated Handgrip Strength Variability in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Separating Disease-Related Fatigability from Force Gradation
BACKGROUND
Force production reflects neuromuscular capacity, central regulation, and sensory feedback, making performance-based testing...
Ozone therapy by rectal insufflation in long COVID syndrome: a preliminary study with thermographic evaluation and quality of life measurement
Abstract
Introduction
Post-acute coronavirus disease 2019 syndrome (PACS) is a multisystemic clinical condition that clinically starting weeks or...
Handgrip strength in children, adolescents, and young adults with suspected myalgic encephalomyelitis/chronic fatigue syndrome
BACKGROUND
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) in children, young people (CYP) lacks validated diagnostic biomarkers. Post-exertional malaise...
Dissociation Between Peripheral Muscle Strength and Exercise Capacity in Symptomatic Post‐COVID‐19 Individuals: Implications for Musculoskeletal Rehabilitation
ABSTRACT
Introduction
Infection with SARS-CoV-2 may result in persistent functional impairment after the acute phase of the disease...
iPSC-Derived Myogenic Progenitor Cells from People with ME/CFS Reveal Altered Genes and Pathways with Drug Repurposing Potential
Nguyen, Dao
Background
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating multisystem disorder characterised by profound fatigue...
Persistent Muscle Dysfunction and Symptom Burden in Post-COVID Syndrome: A Prospective Longitudinal Study
BACKGROUND
Post-COVID syndrome (PCS) is characterized by persistent heterogeneous symptoms after SARS-CoV-2 infection, yet objective biomarkers for symptom severity and longitudinal...
Central noradrenergic deficiency in post-infectious chronic fatigue: neurobehavioral correlates
Abstract
Fatigue, brain fog, and post-exertional malaise are major features of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome and post-acute sequelae of severe acute respiratory...
Interpreting hand grip strength in hospital employees with post-COVID syndrome compared to non-infected controls: a case-control study
Abstract
Post-COVID syndrome (PCS) is characterized by a variety of persistent symptoms following SARS-CoV-2 infection, including fatigue among others...
Assessment of physical status and analysis of lipidomic and metabolomic alterations in patients with Post-COVID-19 condition
The development and persistence of symptoms following SARS-CoV-2 infection, known as Post-COVID-19 Condition (PCC) or “long COVID,” represents a global health challenge...
Now published - link here
Preprint
Hyperbaric oxygen therapy improves clinical symptoms and functional capacity and restores thalamic connectivity in ME/CFS
BACKGROUND
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disorder characterized by profound fatigue...
Variation in Repeated Handgrip Strength Testing Indicates Submaximal Force Production in Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Stoyan Popkirov
Background
Changes in handgrip strength have recently been adapted as clinical biomarkers for myalgic...
https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2025.1637838/abstract
Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a multisystemic disease characterized by exertional intolerance and fatigue which is often accompanied by muscleweakness and...
Effects of a symptom-titrated exercise program on fatigue and quality of life in people with post-COVID condition – a randomized controlled trial
Barz, Andreas; Berger, Joshua; Speicher, Marco; Morsch, Arne; Wanjek, Markus; Rissland, Jürgen; Jäger, Johannes
Fatigue is the most prevalent symptom...
https://www.mdpi.com/1648-9144/60/8/1370
A Multimodal Magnetic Resonance Imaging Study on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Feasibility and Clinical Correlation
Abstract
Background/Objectives:
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a neurological...
Insights into COVID-19 pathophysiology from a longitudinal multisystem report during acute infection
Brihmat; Bayram; Bheemreddy; Saleh; Yue; Forrest
The Coronavirus disease 2019 (COVID-19), an illness caused by a SARS-CoV-2 viral infection, has been associated with neurological and...
Full title:
Impaired Hand Grip Strength Correlates with Greater Disability and Symptom Severity in Post-COVID Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
https://www.mdpi.com/2077-0383/13/7/2153
Abstract
Post-COVID syndrome (PCS) encompasses a diverse array of symptoms persisting beyond...
This post has been copied and many following posts moved from the main thread on the study:
Deep phenotyping of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome, 2024, Walitt et al
Abstract
Post-infectious myalgic encephalomyelitis/chronic fatigue syndrome (PI-ME/CFS) is a...
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