herpesvirus

[...] Herpesviruses and a Faulty Antiviral Response may Contribute to Chronic Multi-Symptom and Multi-System Illnesses in U.S. Military Veterans Brandon Cox, Paula Goolkasian, Irene Mena Palomo, Marshall V. Williams, Sean R. Maloney, Maria Eugenia Ariza [Line breaks added] ABSTRACT Chronic...

Editor’s summary Infection with herpes simplex virus type 1 (HSV-1) is common, lifelong, and often in a latent state with periodic reactivation. It is a risk factor for neurodegenerative disease and dementia in some individuals, as are repeated head injuries like concussions. Cairns et al. found...

Full title: From human herpes virus-6 reactivation to autoimmune reactivity against tight junctions and neuronal antigens, to inflammation, depression, and chronic fatigue syndrome due to Long COVID Abstract Inflammation and autoimmune responses contribute to the pathophysiology of Long COVID...

Abstract Myalgic Encephalomyelitis / Chronic Fatigue Syndrome is a debilitating, multisystem disease of unknown mechanism, with a currently ongoing search for its endocrine mediators. Circulating microRNAs (miRNA) are a promising candidate for such a mediator and have been reported as...

The viral origin of myalgic encephalomyelitis/chronic fatigue syndrome Maureen R. Hanson Sections — Can any infection lead to ME/CFS? Why is the enterovirus family the most likely culprit in ME/CFS? What is the relationship between human herpesviruses (HHVs) and ME/CFS? Should the...

The incidence of human herpesvirus (HHVs) is gradually increasing and has affected a wide range of population. HHVs can result in serious consequences such as tumors, neonatal malformations, sexually transmitted diseases, as well as pose an immense threat to the human health. The cGAS-STING...

Recognition of herpesviruses by the innate immune system Paludan, Søren R.; Bowie, Andrew G.; Horan, Kristy A.; Fitzgerald, Katherine A. Advances in innate immunity over the past decade have revealed distinct classes of pattern recognition receptors (PRRs) that detect pathogens at the cell...

Latent virus reactivation in astronauts on the international space station Mehta, Satish K.; Laudenslager, Mark L.; Stowe, Raymond P.; Crucian, Brian E.; Feiveson, Alan H.; Sams, Clarence F.; Pierson, Duane L. Reactivation of latent herpes viruses was measured in 23 astronauts (18 male and 5...

Kaposi's sarcoma-associated herpesvirus (KSHV) utilizes the NDP52/CALCOCO2 selective autophagy receptor to disassemble processing bodies Robinson CA, Singh GK, Kleer M, Katsademas T, Castle EL, Boudreau BQ, Corcoran JA Kaposi’s sarcoma-associated herpesvirus (KSHV) causes the inflammatory and...

Potent Antiviral Activity against HSV-1 and SARS-CoV-2 by Antimicrobial Peptoids Diamond G, Molchanova N, Herlan C, Fortkort JA, Lin JS, Figgins E, Bopp N, Ryan LK, Chung D, Adcock RS, Sherman M, Barron AE Viral infections, such as those caused by Herpes Simplex Virus-1 (HSV-1) and SARS-CoV-2...

https://www.brunel.ac.uk/research/projects/reactivation-of-herpesviruses-in-chronic-fatigue-syndrome

Abstract Herpesviruses have mastered host cell modulation and immune evasion to augment productive infection, life-long latency and reactivation1,2. A long appreciated, yet undefined relationship exists between the lytic–latent switch and viral non-coding RNAs3,4. Here we identify viral...

Abstract Fast-replicating neurotropic herpesviruses exemplified by herpes simplex virus-1 (HSV-1) naturally infect the central nervous system (CNS). However, most individuals intrinsically suppress the virus during a primary infection and preclude it from significantly damaging the CNS...

Abstract Introduction: Chronic fatigue syndrome (CFS) is a neurological disease that is accompanied by excessive fatigue or tiredness. There are several reports confirming the association between Human Herpesvirus 6 (HHV-6) infection and CFS illness. This systematic review and meta-analysis...

Note:this article is provisionally accepted Abstract: The evidence of an association between Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and chronic herpesviruses infections remains inconclusive. Two possible reasons for this lack of consistent evidence are the large...

Preprint. " Abstract Finite mixture models have been widely used in antibody (or serological) data analysis in order to help classifying individuals into either antibody-positive or antibody-negative. The most popular models are the so-called Gaussian mixture models which assume a Normal...

https://www.mdpi.com/2218-273X/11/2/185

Dana M. Cairns [1,2], Nicolas Rouleau [1,2], Rachael N. Parker [1], Katherine G. Walsh [3], Lee Gehrke [4] and David L. Kaplan [1,2]* 1. Department of Biomedical Engineering, Tufts University, Medford, MA 02155, USA. 2. Allen Discovery Center, Tufts University, Medford, MA 02155, USA. 3...

Free full text: https://kb.osu.edu/bitstream/handle/1811/91637/julia_hasik_thesis_20200424.pdf?sequence=1&isAllowed=y

by Philipp Schreiner, Thomas Harrer, Carmen Scheibenbogen, Stephanie Lamer, Andreas Schlosser, Robert K. Naviaux and Bhupesh K. Prusty Published in ImmunoHorizons Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a multifactorial disorder with many possible triggers...