herpesvirus

Alzheimer’s disease can begin almost imperceptibly, often masquerading in the early months or years as forgetfulness that is common in older age. What causes the disease remains largely a mystery. But researchers at Tufts University and the University of Oxford, using a three-dimensional human...

Abstract Herpesviruses have mastered host cell modulation and immune evasion to augment productive infection, life-long latency and reactivation1,2. A long appreciated, yet undefined relationship exists between the lytic–latent switch and viral non-coding RNAs3,4. Here we identify viral...

vvv Source: Medical Immunology Vol 23, #4, pp 975-980 Date: July/August 2021 URL: https://www.mimmun.ru/mimmun/article/view/2439 https://www.mimmun.ru/mimmun/article/view/2439/1456 Early diagnostics of autoinflammatory disorders associated with post-viral chronic fatigue...

Abstract Fast-replicating neurotropic herpesviruses exemplified by herpes simplex virus-1 (HSV-1) naturally infect the central nervous system (CNS). However, most individuals intrinsically suppress the virus during a primary infection and preclude it from significantly damaging the CNS...

In mice. Abstract Epstein-Barr virus (EBV) infection is associated with rheumatoid arthritis (RA) in adults, though the nature of the relationship remains unknown. Herein, we have examined the contribution of viral infection to the severity of arthritis in mice. We have provided the first...

Abstract Introduction: Chronic fatigue syndrome (CFS) is a neurological disease that is accompanied by excessive fatigue or tiredness. There are several reports confirming the association between Human Herpesvirus 6 (HHV-6) infection and CFS illness. This systematic review and meta-analysis...

Note:this article is provisionally accepted Abstract: The evidence of an association between Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and chronic herpesviruses infections remains inconclusive. Two possible reasons for this lack of consistent evidence are the large...

Preprint. " Abstract Finite mixture models have been widely used in antibody (or serological) data analysis in order to help classifying individuals into either antibody-positive or antibody-negative. The most popular models are the so-called Gaussian mixture models which assume a Normal...

Paywall, https://link.springer.com/article/10.1007/s13365-021-00952-6

Myalgic encephalomyelitis/chronic fatigue syndrome and gulf war illness patients exhibit increased humoral responses to the herpesviruses-encoded dUTPase: Implications in disease pathophysiology Peter Halpin 1, Marshall Vance Williams 1 2, Nancy G Klimas 3 4, Mary Ann Fletcher 3 4, Zachary...

https://www.mdpi.com/2218-273X/11/2/185

Full title: Salivary DNA loads for human herpes viruses 6 and 7 are correlated with disease phenotype in Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome https://www.medrxiv.org/content/10.1101/2021.01.06.20248486v1

This study received significant funding from the US NIH but it doesn't seem a paper will be published. I'm guessing they only received funding for R21 to do feasibility work and that work allowed them to develop a test but only test a small cohort. US NIH Project Description Source ...

Dana M. Cairns [1,2], Nicolas Rouleau [1,2], Rachael N. Parker [1], Katherine G. Walsh [3], Lee Gehrke [4] and David L. Kaplan [1,2]* 1. Department of Biomedical Engineering, Tufts University, Medford, MA 02155, USA. 2. Allen Discovery Center, Tufts University, Medford, MA 02155, USA. 3...

Free full text: https://kb.osu.edu/bitstream/handle/1811/91637/julia_hasik_thesis_20200424.pdf?sequence=1&isAllowed=y

by Philipp Schreiner, Thomas Harrer, Carmen Scheibenbogen, Stephanie Lamer, Andreas Schlosser, Robert K. Naviaux and Bhupesh K. Prusty Published in ImmunoHorizons Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a multifactorial disorder with many possible triggers...

Paywall, https://onlinelibrary.wiley.com/doi/pdf/10.1002/jmv.25744 Not available via Sci hub at time of posting.

Open access, https://www.frontiersin.org/articles/10.3389/fimmu.2019.02715/full Press release, https://eurekalert.org/pub_releases/2019-11/ki-mlt112519.php

Nuno Sepúlveda, Jorge Carneiro, Eliana M. Lacerda and Luis C. Nacul https://www.frontiersin.org/articles/10.3389/fimmu.2019.02684/abstract Study made with the UK ME/CFS Biobank Full text not available yet, will be published soon.