innate immune system

  1. SNT Gatchaman

    Immunogenicity of lipid nanoparticles and its impact on the efficacy of mRNA vaccines and therapeutics, 2023, Lee et al.

    Immunogenicity of lipid nanoparticles and its impact on the efficacy of mRNA vaccines and therapeutics Lee, Yeji; Jeong, Michaela; Park, Jeongeun; Jung, Hyein; Lee, Hyukjin Several studies have utilized a lipid nanoparticle delivery system to enhance the effectiveness of mRNA therapeutics and...
  2. SNT Gatchaman

    Helicobacter pylori induces a novel form of innate immune memory via accumulation of NF-кB proteins, 2023, Frauenlob et al.

    Helicobacter pylori induces a novel form of innate immune memory via accumulation of NF-кB proteins Frauenlob, Tobias; Neuper, Theresa; Regl, Christof; Schaepertoens, Veronika; Unger, Michael S.; Oswald, Anna-Lena; Dang, Hieu-Hoa; Huber, Christian G.; Aberger, Fritz; Wessler, Silja...
  3. SNT Gatchaman

    [Preprint] Evolutionary arms race between SARS-CoV-2 and interferon signaling via dynamic interaction with autophagy, 2023, Lee et al.

    Evolutionary arms race between SARS-CoV-2 and interferon signaling via dynamic interaction with autophagy Jae Seung Lee; Mark Dittmar; Jesse Miller; Minghua Li; Kasirajan Ayyanathan; Max B Ferretti; Jesse Hulahan; Kanupriya Whig; Zienab Etwebi; Trevor Griesman; David C. Schultz; Sara Cherry...
  4. SNT Gatchaman

    Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia, 2023, Garza et al.

    Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia Raquel Garza; Yogita Sharma; Diahann A.M. Atacho; Arun Thiruvalluvan; Sami Abu Hamdeh; Marie E. Jönsson; Vivien Horvath; Anita Adami; Martin Ingelsson; Patric Jern; Molly...
    • SNT Gatchaman
    • Thread
    • herv herv-k herv-w innate immune system interferon microglia neuroinflammation oligodendrocytes single-cell transcriptomics traumatic brain injury
    • Replies: 6
    • Forum: Other health news and research
  5. SNT Gatchaman

    Review Genomic communication via circulating extracellular vesicles and long-term health consequences of COVID-19, 2023, Nair et al.

    Genomic communication via circulating extracellular vesicles and long-term health consequences of COVID-19 Nair, Soumyalekshmi; Nova-Lamperti, Estefania; Labarca, Gonzalo; Kulasinghe, Arutha; Short, Kirsty R.; Carrión, Flavio; Salomon, Carlos COVID-19 continues to affect an unprecedented number...
    • SNT Gatchaman
    • Thread
    • epigenetics extracellular vesicles gene expression glucose innate immune system lipid metabolism long covid metabolism sars-cov-2 spike protein thrombosis
    • Replies: 0
    • Forum: Long Covid research
  6. SNT Gatchaman

    Epigenetic memory of coronavirus infection in innate immune cells and their progenitors, 2023, Cheong et al.

    Epigenetic memory of coronavirus infection in innate immune cells and their progenitors Jin-Gyu Cheong; Arjun Ravishankar; Siddhartha Sharma; Christopher N. Parkhurst; Simon A. Grassmann; Claire K. Wingert; Paoline Laurent; Sai Ma; Lucinda Paddock; Isabella C. Miranda; Emin Onur Karakaslar...
    • SNT Gatchaman
    • Thread
    • bone marrow covid-19 epigenetics haematopoietic stem cell progenitors hspc il-6 immune dysfunction innate immune system monocytes stem cells trained innate immunity
    • Replies: 6
    • Forum: Long Covid research
  7. SNT Gatchaman

    Exploring microplastic impact on whole blood clotting dynamics utilizing thromboelastography, 2023, Christodoulides et al.

    Exploring microplastic impact on whole blood clotting dynamics utilizing thromboelastography Christodoulides, Alexei; Hall, Abigail; Alves, Nathan J. This study investigates the influence of microplastics on blood clotting. It addresses the lack of comprehensive research on the effects of...
  8. SNT Gatchaman

    Recognition of herpesviruses by the innate immune system, 2011, Paludan et al.

    Recognition of herpesviruses by the innate immune system Paludan, Søren R.; Bowie, Andrew G.; Horan, Kristy A.; Fitzgerald, Katherine A. Advances in innate immunity over the past decade have revealed distinct classes of pattern recognition receptors (PRRs) that detect pathogens at the cell...
  9. SNT Gatchaman

    The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity, 2015, Heinz et al.

    The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity Heinz; Baumann; Köberlin; Snijder; Gawish; Shui; Sharif; Aspalter; Müller; Kandasamy; Breitwieser; Pichlmair; Bruckner; Rebsamen; Blüml; Karonitsch; Fauster; Colinge; Bennett; Knapp; Superti-Furga Lipid metabolism and...
  10. SNT Gatchaman

    The Pathological Activation of Microglia Is Modulated by Sexually Dimorphic Pathways, 2023, O'Connor et al.

    The Pathological Activation of Microglia Is Modulated by Sexually Dimorphic Pathways O'Connor, Jennifer L.; Nissen, Jillian C. Microglia are the primary immunocompetent cells of the central nervous system (CNS). Their ability to survey, assess and respond to perturbations in their local...
  11. SNT Gatchaman

    Innate immune cell activation causes lung fibrosis in a humanized model of long COVID, 2023, Cui et al

    Innate immune cell activation causes lung fibrosis in a humanized model of long COVID Lu Cui, Zhuoqing Fang, Cristabelle Madona De Souza, Tristan Lerbs, Yuan Guan, Irene Li, Vivek Charu, Shih-Yu Chen, Irving Weissman, Gerlinde Wernig COVID-19 remains a global pandemic of an unprecedented...
  12. Andy

    A patient-centric modeling framework captures recovery from SARS-CoV-2 infection, 2023, Ruffieux et al

    Abstract The biology driving individual patient responses to severe acute respiratory syndrome coronavirus 2 infection remains ill understood. Here, we developed a patient-centric framework leveraging detailed longitudinal phenotyping data and covering a year after disease onset, from 215...
    • Andy
    • Thread
    • innate immune system kynurenine lipidomics long covid metabolomics nicholson nk cells
    • Replies: 7
    • Forum: Long Covid research
  13. SNT Gatchaman

    Recovering or Persisting: The Immunopathological Features of SARS-CoV-2 Infection in Children, 2022, Buonsenso et al

    Recovering or Persisting: The Immunopathological Features of SARS-CoV-2 Infection in Children Buonsenso D, Valentini P, De Rose C, Tredicine M, Pereyra Boza MdC, Camponeschi C, Morello R, Zampino G, Brooks AES, Rende M, Ria F, Sanguinetti M, Delogu G, Sali M, Di Sante G, on behalf of the...
    • SNT Gatchaman
    • Thread
    • children covid-19 immune dysfunction immunology innate immune system long covid t cells
    • Replies: 2
    • Forum: Long Covid research
  14. SNT Gatchaman

    Tryptophan and the innate intestinal immunity: Crosstalk between metabolites, host innate immune cells, and microbiota: 2022, Li et al

    Tryptophan and the innate intestinal immunity: Crosstalk between metabolites, host innate immune cells, and microbiota Yunke Li, Ning Liu, Yao Ge, Ying Yang, Fazheng Ren, Zhenlong Wu Abstract The intestinal mucosal barrier is critical for the absorption of nutrients and the health of both...
  15. leokitten

    The deubiquitinase MYSM1 dampens NOD2-mediated inflammation and tissue damage by inactivating the RIP2 complex

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220254/ Very interesting paper which has identified MYSM1, a part of the ubiquitin system that acts as a molecular switch to deactivate the innate immune system and has the ability to prevent certain diseases caused by an excessive activation of the...
Back
Top