innate immune system

  1. SNT Gatchaman

    APOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microglia, 2024, Haney et al.

    APOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microglia Haney, Michael S.; Pálovics, Róbert; Munson, Christy Nicole; Long, Chris; Johansson, Patrik K.; Yip, Oscar; Dong, Wentao; Rawat, Eshaan; West, Elizabeth; Schlachetzki, Johannes C. M.; Tsai, Andy; Guldner, Ian Hunter...
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    • alzheimers amyloid amyloid plaque apoe genetic innate immune system lipid droplets lipids microglia neurodegenerative disease risk factors
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    • Forum: Other health news and research
  2. SNT Gatchaman

    Review Rethinking coagulation: from enzymatic cascade and cell-based reactions to a convergent model involving innate immune activation, 2023, Yong, Jun and

    Rethinking coagulation: from enzymatic cascade and cell-based reactions to a convergent model involving innate immune activation Yong, Jun; Toh, Cheng-Hock Advancements in the conceptual thinking of hemostasis and thrombosis have been catalyzed by major developments within health research over...
  3. SNT Gatchaman

    Review Systems analysis of innate and adaptive immunity in Long COVID, 2024, Peluso et al.

    Systems analysis of innate and adaptive immunity in Long COVID Peluso; Abdel-Mohsen; Henrich; Roan Since the onset of the COVID-19 pandemic, significant progress has been made in developing effective preventive and therapeutic strategies against severe acute SARS-CoV-2 infection. However, the...
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    • b cells immune system immunoglobulin innate immune system long covid system biology t cells
    • Replies: 2
    • Forum: Long Covid research
  4. SNT Gatchaman

    Review Defining trained immunity and its role in health and disease, 2020, Netea et al.

    Defining trained immunity and its role in health and disease Netea, Mihai G.; Domínguez-Andrés, Jorge; Barreiro, Luis B.; Chavakis, Triantafyllos; Divangahi, Maziar; Fuchs, Elaine; Joosten, Leo A. B.; van der Meer, Jos W. M.; Mhlanga, Musa M.; Mulder, Willem J. M.; Riksen, Niels P.; Schlitzer...
  5. SNT Gatchaman

    Review Functional Reciprocity of Amyloids & Antimicrobial Peptides: Rethinking the Role of Supramolecular Assembly in Host Defense, Immune Activation…, 2020

    Functional Reciprocity of Amyloids and Antimicrobial Peptides: Rethinking the Role of Supramolecular Assembly in Host Defense, Immune Activation, and Inflammation Lee EY; Srinivasan Y; de Anda J; Nicastro LK; Tükel Ç; Wong GCL; Pathological self-assembly is a concept that is classically...
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    Evolution of enhanced innate immune suppression by SARS-CoV-2 Omicron subvariants, 2024, Towers et al

    Evolution of enhanced innate immune suppression by SARS-CoV-2 Omicron subvariants Nature, open access: https://www.nature.com/articles/s41564-023-01588-4 Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) human adaptation resulted in distinct lineages with enhanced...
  7. SNT Gatchaman

    Preprint Transcriptional memory is conferred by combined heritable maintenance and local removal of selective chromatin modifications, 2023, Mikulski et al.

    Transcriptional memory is conferred by combined heritable maintenance and local removal of selective chromatin modifications Pawel Mikulski; Sahar S.H. Tehrani; Anna Kogan; Izma Abdul-Zani; Emer Shell; Brent J Ryan; Lars E.T. Jansen Interferon-γ (IFNγ) transiently activates genes involved in...
  8. SNT Gatchaman

    Sex-dependent differences in type I IFN-induced natural killer cell activation, 2023, Pujantell et al.

    Sex-dependent differences in type I IFN-induced natural killer cell activation Pujantell, Maria; Skenteris, Nikolaos-Taxiarchis; Claussen, Janna Marieke; Grünhagel, Benjamin; Thiele, Rebecca-Jo; Altfeld, Marcus Natural killer (NK) cells are important antiviral effector cells and also involved...
  9. SNT Gatchaman

    Proteomic Evolution from Acute to Post-COVID-19 Conditions, 2023, Mohammed et al.

    Proteomic Evolution from Acute to Post-COVID-19 Conditions Yassene Mohammed; Karen Tran; Chris Carlsten; Christopher Ryerson; Alyson Wong; Terry Lee; Matthew P. Cheng; Donald C. Vinh; Todd C. Lee; Brent W. Winston; David Sweet; John H. Boyd; Keith R. Walley; Greg Haljan; Allison McGeer; Francois...
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    • fibronectin innate immune system lipid metabolism long covid proteomics vasoconstriction
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    • Forum: Long Covid research
  10. SNT Gatchaman

    Immunogenicity of lipid nanoparticles and its impact on the efficacy of mRNA vaccines and therapeutics, 2023, Lee et al.

    Immunogenicity of lipid nanoparticles and its impact on the efficacy of mRNA vaccines and therapeutics Lee, Yeji; Jeong, Michaela; Park, Jeongeun; Jung, Hyein; Lee, Hyukjin Several studies have utilized a lipid nanoparticle delivery system to enhance the effectiveness of mRNA therapeutics and...
  11. SNT Gatchaman

    Helicobacter pylori induces a novel form of innate immune memory via accumulation of NF-кB proteins, 2023, Frauenlob et al.

    Helicobacter pylori induces a novel form of innate immune memory via accumulation of NF-кB proteins Frauenlob, Tobias; Neuper, Theresa; Regl, Christof; Schaepertoens, Veronika; Unger, Michael S.; Oswald, Anna-Lena; Dang, Hieu-Hoa; Huber, Christian G.; Aberger, Fritz; Wessler, Silja...
  12. SNT Gatchaman

    [Preprint] Evolutionary arms race between SARS-CoV-2 and interferon signaling via dynamic interaction with autophagy, 2023, Lee et al.

    Evolutionary arms race between SARS-CoV-2 and interferon signaling via dynamic interaction with autophagy Jae Seung Lee; Mark Dittmar; Jesse Miller; Minghua Li; Kasirajan Ayyanathan; Max B Ferretti; Jesse Hulahan; Kanupriya Whig; Zienab Etwebi; Trevor Griesman; David C. Schultz; Sara Cherry...
  13. SNT Gatchaman

    Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia, 2023, Garza et al.

    Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia Raquel Garza; Yogita Sharma; Diahann A.M. Atacho; Arun Thiruvalluvan; Sami Abu Hamdeh; Marie E. Jönsson; Vivien Horvath; Anita Adami; Martin Ingelsson; Patric Jern; Molly...
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    • herv herv-k herv-w innate immune system interferon microglia neuroinflammation oligodendrocytes single-cell transcriptomics traumatic brain injury
    • Replies: 6
    • Forum: Other health news and research
  14. SNT Gatchaman

    Review Genomic communication via circulating extracellular vesicles and long-term health consequences of COVID-19, 2023, Nair et al.

    Genomic communication via circulating extracellular vesicles and long-term health consequences of COVID-19 Nair, Soumyalekshmi; Nova-Lamperti, Estefania; Labarca, Gonzalo; Kulasinghe, Arutha; Short, Kirsty R.; Carrión, Flavio; Salomon, Carlos COVID-19 continues to affect an unprecedented number...
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    • epigenetics extracellular vesicles gene expression glucose innate immune system lipid metabolism long covid metabolism sars-cov-2 spike protein thrombosis
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    • Forum: Long Covid research
  15. SNT Gatchaman

    Epigenetic memory of coronavirus infection in innate immune cells and their progenitors, 2023, Cheong et al.

    Epigenetic memory of coronavirus infection in innate immune cells and their progenitors Jin-Gyu Cheong; Arjun Ravishankar; Siddhartha Sharma; Christopher N. Parkhurst; Simon A. Grassmann; Claire K. Wingert; Paoline Laurent; Sai Ma; Lucinda Paddock; Isabella C. Miranda; Emin Onur Karakaslar...
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    • bone marrow covid-19 epigenetics haematopoietic stem cell progenitors hspc il-6 immune dysfunction innate immune system monocytes stem cells trained innate immunity
    • Replies: 6
    • Forum: Long Covid research
  16. SNT Gatchaman

    Exploring microplastic impact on whole blood clotting dynamics utilizing thromboelastography, 2023, Christodoulides et al.

    Exploring microplastic impact on whole blood clotting dynamics utilizing thromboelastography Christodoulides, Alexei; Hall, Abigail; Alves, Nathan J. This study investigates the influence of microplastics on blood clotting. It addresses the lack of comprehensive research on the effects of...
  17. SNT Gatchaman

    Recognition of herpesviruses by the innate immune system, 2011, Paludan et al.

    Recognition of herpesviruses by the innate immune system Paludan, Søren R.; Bowie, Andrew G.; Horan, Kristy A.; Fitzgerald, Katherine A. Advances in innate immunity over the past decade have revealed distinct classes of pattern recognition receptors (PRRs) that detect pathogens at the cell...
  18. SNT Gatchaman

    The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity, 2015, Heinz et al.

    The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity Heinz; Baumann; Köberlin; Snijder; Gawish; Shui; Sharif; Aspalter; Müller; Kandasamy; Breitwieser; Pichlmair; Bruckner; Rebsamen; Blüml; Karonitsch; Fauster; Colinge; Bennett; Knapp; Superti-Furga Lipid metabolism and...
  19. SNT Gatchaman

    The Pathological Activation of Microglia Is Modulated by Sexually Dimorphic Pathways, 2023, O'Connor et al.

    The Pathological Activation of Microglia Is Modulated by Sexually Dimorphic Pathways O'Connor, Jennifer L.; Nissen, Jillian C. Microglia are the primary immunocompetent cells of the central nervous system (CNS). Their ability to survey, assess and respond to perturbations in their local...
  20. SNT Gatchaman

    Innate immune cell activation causes lung fibrosis in a humanized model of long COVID, 2023, Cui et al

    Innate immune cell activation causes lung fibrosis in a humanized model of long COVID Lu Cui, Zhuoqing Fang, Cristabelle Madona De Souza, Tristan Lerbs, Yuan Guan, Irene Li, Vivek Charu, Shih-Yu Chen, Irving Weissman, Gerlinde Wernig COVID-19 remains a global pandemic of an unprecedented...
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