macrophages

  1. Mij

    Single-cell RNA-Seq reveals intracellular microbial diversity within immune cells during SARS-CoV-2 infection and recovery, 2023, Sunita Yadav et al

    Highlights 76 bacterial species of 15 genera across healthy, COVID-19-positive, and recovered individuals Higher abundance of opportunistic intracellular bacteria in recovered group Higher microbial abundance within antigen-presenting cells of COVID-19 patients Differential microbial abundance...
    • Mij
    • Thread
    • b cells covid dendritic cells innate immune response intracellular infection intracellular pathogen macrophages monocytes nk cells pbmc plasma cells platelets single-cell transcriptomics t cells
    • Replies: 6
    • Forum: Epidemics (including Covid-19, not Long Covid)
  2. SNT Gatchaman

    Preprint Transcriptional memory is conferred by combined heritable maintenance and local removal of selective chromatin modifications, 2023, Mikulski et al.

    Transcriptional memory is conferred by combined heritable maintenance and local removal of selective chromatin modifications Pawel Mikulski; Sahar S.H. Tehrani; Anna Kogan; Izma Abdul-Zani; Emer Shell; Brent J Ryan; Lars E.T. Jansen Interferon-γ (IFNγ) transiently activates genes involved in...
  3. SNT Gatchaman

    Alterations to Sphingomyelin Metabolism Affect Hemostasis and Thrombosis, 2023, Wang et al.

    Alterations to Sphingomyelin Metabolism Affect Hemostasis and Thrombosis Jue Wang; Shiva Keshava; Kaushik Das; Richard Kolesnick; Xian-Cheng Jiang; Usha R. Pendurthi; L. Vijaya Mohan Rao BACKGROUND: Our recent studies suggest that sphingomyelin levels in the plasma membrane influence TF (tissue...
  4. E

    SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells, 2023, Huot et al

    SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA generally becomes undetectable in upper airways after a few days or weeks postinfection. Here we used a model of viral...
    • EndME
    • Thread
    • animal study fibronectin interferon interferon-y lungs macrophages nk cells t cells viral persistence
    • Replies: 4
    • Forum: Long Covid research
  5. SNT Gatchaman

    Metabolic regulation of gene expression by histone lactylation, 2019, Zhang et al.

    Metabolic regulation of gene expression by histone lactylation Zhang, Di; Tang, Zhanyun; Huang, He; Zhou, Guolin; Cui, Chang; Weng, Yejing; Liu, Wenchao; Kim, Sunjoo; Lee, Sangkyu; Perez-Neut, Mathew; Ding, Jun; Czyz, Daniel; Hu, Rong; Ye, Zhen; He, Maomao; Zheng, Y. George; Shuman, Howard A...
  6. SNT Gatchaman

    Review Lactic acid in macrophage polarization: The significant role in inflammation and cancer, 2021, Zhou et al.

    Lactic acid in macrophage polarization: The significant role in inflammation and cancer Hai-cun Zhou; Xin-yan Yan ; Wen-wen Yu; Xiao-qin Liang; Xiao-yan Du; Zhi-chang Liu; Jian-ping Long; Guang-hui Zhao; Hong-bin Liu Metabolite lactic acid has always been regarded as a metabolic by-product...
  7. SNT Gatchaman

    The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity, 2015, Heinz et al.

    The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity Heinz; Baumann; Köberlin; Snijder; Gawish; Shui; Sharif; Aspalter; Müller; Kandasamy; Breitwieser; Pichlmair; Bruckner; Rebsamen; Blüml; Karonitsch; Fauster; Colinge; Bennett; Knapp; Superti-Furga Lipid metabolism and...
  8. SNT Gatchaman

    Post-COVID exercise intolerance ...associated ... capillary alterations and immune dysregulations in skeletal muscles, 2023, Aschman, Scheibenbogen +

    Now published - see post Preprint Post-COVID syndrome is associated with capillary alterations, macrophage infiltration and distinct transcriptomic signatures in skeletal muscles Tom Aschman, Emanuel Wyler, Oliver Baum, Andreas Hentschel, Franziska Legler, Corinna Preusse, Lil Meyer-Arndt...
    • SNT Gatchaman
    • Thread
    • capillaries capillary basement thickness cd169 immune dysfunction long covid macrophages microcirculation muscle muscle biopsy muscle weakness t-cells
    • Replies: 12
    • Forum: Long Covid research
  9. SNT Gatchaman

    [Preprint] Liquid biomarkers of macrophage dysregulation & circulating spike protein illustrate the biological heterogeneity in patients with LC, 2022

    Liquid biomarkers of macrophage dysregulation and circulating spike protein illustrate the biological heterogeneity in patients with post-acute sequelae of COVID-19 Christoph Schultheiss, Edith Willscher, Lisa Paschold, Cornelia Gottschick, Bianca Klee, Lidia Bosurgi, Jochen Dutzmann, Daniel...
  10. SNT Gatchaman

    A macrophage attack culminating in microthromboses characterizes COVID 19 pneumonia, 2021, Bull et al

    A macrophage attack culminating in microthromboses characterizes COVID 19 pneumonia Brian S Bull, Karen L Hay Introduction: A neutrophilic infiltrate characterizes bacterial pneumonia. Macrophage infiltration is similarly characteristic of the viral pneumonia caused by SARS-CoV-2. These...
  11. Andy

    Bile acid-activated receptors and the regulation of macrophages function in metabolic disorders, 2020, Fiorucci et al

    Paywall, https://www.sciencedirect.com/science/article/abs/pii/S1471489220300175 Sci hub, https://sci-hub.tw/10.1016/j.coph.2020.04.008
  12. Andy

    Mitochondria Play an Unexpected Role in Killing Bacteria

    https://www.the-scientist.com/the-literature/mitochondria-play-an-unexpected-role-in-killing-bacteria-65246
    • Andy
    • Thread
    • immunology macrophages mitochondria mitochondrial function pathogens reactive oxygen species white blood cells
    • Replies: 6
    • Forum: Other health news and research
  13. Andy

    Effects of anti-inflammatory drugs on the expression of tryptophan-metabolism genes by human macrophages, 2018, Freeman et al

    Open access at https://www.researchgate.net/publication/322727729_Effects_of_anti-inflammatory_drugs_on_the_expression_of_tryptophan-metabolism_genes_by_human_macrophages
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