From Dr Mark Guthridge' s twitter feed.
Currently used for MS, mechanism being unravelled
Using metabolism to dampen autoimmune response
http://science.sciencemag.org/content/360/6387/377
Has anyone got access to the full paper?
http://www.biochemsoctrans.org/content/early/2018/04/16/BST20170503
Metabolic abnormalities in chronic fatigue syndrome/myalgic encephalomyelitis: a mini-review
Cara Tomas, Julia Newton
Biochemical Society Transactions Apr 17, 2018, BST20170503; DOI...
Have had limited success with the search function here, so if this has been posted already, please delete.
Abstract
Link to full study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365380/
http://journals.sagepub.com/doi/abs/10.1177/1742395317746470
Energy envelope maintenance among patients with myalgic encephalomyelitis and chronic fatigue syndrome: Implications of limited energy reserves
Kelly O'connor(1), Madison Sunnquist(1), Laura Nicholson(1),
Leonard A Jason(1), Julia L...
I wasn’t sure where to put this. It is general background information about metabolism, but since it is directly relevant to energy production in PWME and hence fatigue, I put it here.
Recently I needed to refresh my memory about how some amino acids are broken down for energy.
I thought I...
Kate E Earl, Giorgos K Sakellariou, Melanie Sinclair, Manuel Fenech, Fiona Croden, Daniel J Owens, Jonathan Tang, Alastair Miller, Clare Lawton, Louise Dye, Graeme L Close, William D Fraser, Anne McArdle, Michael B J Beadsworth
Abstract
Objective Severe vitamin D deficiency is a recognised...
Main studies
Mitochondrial enzymes discriminate between mitochondrial disorders and chronic fatigue syndrome.
Smits B, van den Heuvel L, Knoop H, Küsters B, Janssen A, Borm G, et al.
Mitochondrion.
2011
Link to article
Metabolic profiling reveals anomalous energy metabolism and oxidative...
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