Abstract The mitochondrial membrane potential (ΔΨm) is a parameter often used to determine mitochondrial function; therefore, it can be used to...
Full title: Does Dietary Coenzyme Q10 plus Selenium Supplementation Ameliorate Clinical Outcomes by Modulating Oxidative Stress and Inflammation...
"Reneo is a clinical stage pharmaceutical company focused on the development and commercialization of therapies for patients with rare genetic...
I put this post here as I couldn't see a section for Primary Mitochondrial Disease in Missed/Alternative Diagnosis section... Given the advice...
not listened to it so no idea of content. In this episode I welcome on Dr. Richard Boles. Dr. Richard G. Boles is a medical geneticist and a...
Full title: Co-Exposure of Cardiomyocytes to IFN-γ and TNF-α Induces Mitochondrial Dysfunction and Nitro-Oxidative Stress: Implications for the...
Posts copied from The micro-clot finding in Long Covid — implications for the possible aetiology of ME/CFS...
Posts moved from this thread: Trial of Long Covid treatment - AXA1125 from Axcella Therapeutics, 2021 ________________ Use of whole genome...
In worms. Abstract Huntington’s disease (HD) is an adult-onset neurodegenerative disease caused by a trinucleotide CAG repeat expansion in the...
Highlights • Mitochondrial respiration decreases with age in PBMCs from healthy individuals. • PBMC mtDNA copy number increases in patients with...
Abstract Porphyromonas gingivalis (P. gingivalis), a key pathogen in periodontitis, has been shown to accelerate the progression of...
biomolecules: Bioenergetic and Proteomic Profiling of Immune Cells in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients: An Exploratory...
Abstract. Estrogen-related receptor gamma (Esrrg) is a murine lupus susceptibility gene associated with T cell activation. Here, we report that...
Highlights • Chronic inflammation can be caused by organelle (e.g., mitochondria) malfunction. • Dysfunctional mitochondria release DAMPs that...
https://doi.org/10.1016/j.cmet.2021.02.017 "Exercise training positively affects metabolic health through increased mitochondrial oxidative...
Abstract Background Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating illness, characterised by persistent fatigue...
Full title: Mitochondria-derived methylmalonic acid, a surrogate biomarker of mitochondrial dysfunction and oxidative stress, predicts all-cause...
Full title: Innate immune signaling and sex differences contribute to neurocognitive impairment, neuroinflammation, and mitochondrial rewiring in...
A SWATH-MS analysis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome peripheral blood mononuclear cell proteomes reveals mitochondrial...
Abstract Chronic fatigue syndrome (CFS) is a complex illness, which is often misdiagnosed as a psychiatric illness. In two previous reports, using...
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