mri

Structural brain abnormalities and neuropsychiatric symptoms in post-COVID condition OBJECTIVES We aimed to cross-sectionally and longitudinally compare brain morphometry and neuropsychiatric symptoms, and evaluate their relationship, in participants with Post-Coronavirus Disease Condition...

Brain MRI findings in patients with post COVID-19 condition: frequency and longitudinal changes in a nationwide cohort study BACKGROUND Prolonged neurological symptoms following COVID-19 are common, yet few longitudinal studies describe brain MRI findings in this patient group. The use of...

Multimodal MRI reveals consistent basal ganglia and limbic system alterations in COVID-19 survivors The long-term impact of COVID-19 on the brain is multifaceted, encompassing structural and functional disruptions. A cohesive theory of the underlying mechanisms of the Post-COVID Syndrome (PCS)...

Relationship between body mass index, gray matter volume and peripheral inflammation in patients with post-COVID condition BACKGROUND Obesity, a condition associated with low-grade peripheral inflammation, is an independent risk factor for severe COVID-19 and has been linked to structural...

Altered brain tissue microstructure and neurochemical profiles in long COVID and recovered COVID-19 individuals: A multimodal MRI study [Line breaks added] Background Diverse neurological symptoms are experienced by long COVID and COVID-19 recovered individuals. However, the long-term...

Creatine kinase imaging CKI for in vivo whole-brain mapping of creatine kinase reaction kinetics The creatine kinase (CK) is a key enzyme involved in brain bioenergetics, playing an important role in brain function and the pathogenesis of neurological and psychiatric diseases and cancers...

Distinct brain alterations and neurodegenerative processes in cognitive impairment associated with post-acute sequelae of COVID-19 Abstract Although brain alterations have been reported in post-acute sequelae of SARS-CoV-2 (PASC), their prevalence and relationship to neurodegeneration remain...

Post-COVID Fatigue Is Associated With Reduced Cortical Thickness After Hospitalization OBJECTIVE Neuropsychiatric symptoms are among the most prevalent sequelae of COVID-19, particularly among hospitalized patients. Recent research has identified volumetric brain changes associated with...

Fatigue in Post-COVID-Condition is accompanied by hypoperfusion of right-occipital areas BACKGROUND AND PURPOSE A proportion of individuals recovering from COVID-19 continue to experience persistent symptoms, including fatigue and cognitive difficulties — a syndrome commonly referred to as...

Longitudinal assessment of pulmonary perfusion and ventilation defects in long COVID: A one-year study using phase-resolved functional lung PREFUL MRI RATIONALE AND OBJECTIVES The long-term trajectories of pulmonary perfusion and ventilation after recovery from SARS-CoV-2 infection are...

Normal appearing white matter and disability in multiple sclerosis BACKGROUND AND OBJECTIVES Multiple sclerosis (MS) is characterized by lesions and atrophy on conventional MRI, yet these often fail to explain disability. Diffusion MRI (dMRI) detects microstructural injury with diffusion...

Attentional failures after sleep deprivation are locked to joint neurovascular, pupil and cerebrospinal fluid flow dynamics Sleep deprivation rapidly disrupts cognitive function and in the long term contributes to neurological disease. Why sleep deprivation has such profound effects on...

Systemic increase of AMPA receptors associated with cognitive impairment of long COVID Long COVID primarily presents with persistent cognitive impairment (Cog-LC), imposing a substantial and lasting global burden. Even after the pandemic, there remains a critical global need for diagnostic and...

Choroid plexus alterations in autism spectrum disorder: A PET-MRI study The choroid plexus (CP), primarily known as the production site of cerebrospinal fluid (CSF), constitutes one of the sites of the blood-CSF barrier and plays a unique role in inflammation propagation, serving as a key...

Varying Levels of Inflammatory Activity in Brain and Body of Patients with Persistent Fatigue and Difficulty Concentrating After COVID-19: A TSPO PET Study A significant number of patients report persistent fatigue and difficulty concentrating after infection with severe acute respiratory...

Abstract: Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex and debilitating condition with a large proportion of patients that experience orthostatic intolerance (OI). This systematic review aimed to assess whether cerebral blood flow (CBF) is reduced in ME/CFS...

Abstract: Large, population-based magnetic resonance imaging (MRI) studies of adolescents promise transformational insights into neurodevelopment and mental illness risk. However, youth MRI studies are especially susceptible to motion and other artifacts that introduce non-random noise. After...

Blood-Brain barrier disruption in long COVID and cognitive correlates: A cross-sectional MRI study Disruption of the blood–brain barrier (BBB) may contribute to neuropsychiatric symptoms observed in Long COVID (LC). Using a non-contrast magnetic resonance imaging (MRI) technique, we...

Ali-Reza Mohammadi-Nejad, Martin Craig, Eleanor F. Cox, Xin Chen, R. Gisli Jenkins, Susan Francis, Stamatios N. Sotiropoulos & Dorothee P. Auer Abstract The impact of SARS-CoV-2 and the COVID-19 pandemic on brain health is recognised, yet specific effects remain understudied. We investigate...