mri

Varying Levels of Inflammatory Activity in Brain and Body of Patients with Persistent Fatigue and Difficulty Concentrating After COVID-19: A TSPO PET Study A significant number of patients report persistent fatigue and difficulty concentrating after infection with severe acute respiratory...

Abstract: Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex and debilitating condition with a large proportion of patients that experience orthostatic intolerance (OI). This systematic review aimed to assess whether cerebral blood flow (CBF) is reduced in ME/CFS...

Abstract: Large, population-based magnetic resonance imaging (MRI) studies of adolescents promise transformational insights into neurodevelopment and mental illness risk. However, youth MRI studies are especially susceptible to motion and other artifacts that introduce non-random noise. After...

Blood-Brain barrier disruption in long COVID and cognitive correlates: A cross-sectional MRI study Disruption of the blood–brain barrier (BBB) may contribute to neuropsychiatric symptoms observed in Long COVID (LC). Using a non-contrast magnetic resonance imaging (MRI) technique, we...

Ali-Reza Mohammadi-Nejad, Martin Craig, Eleanor F. Cox, Xin Chen, R. Gisli Jenkins, Susan Francis, Stamatios N. Sotiropoulos & Dorothee P. Auer Abstract The impact of SARS-CoV-2 and the COVID-19 pandemic on brain health is recognised, yet specific effects remain understudied. We investigate...

Evidence for a role of skull bone marrow in human chronic pain as revealed by TSPO PET imaging The skull bone marrow is emerging as a critical hub for neuroimmune signaling in various disorders, with the potential to reshape how we understand brain-immune interactions. However, its role in...

Abstract While post-infectious (PI-ME/CFS) and gradual onset (GO-ME/CFS) myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) manifest similar symptoms, it has long been suspected that different disease processes underlie them. However, the lack of biological evidence has left this...

Long term effect of COVID-19 on brain metabolism and connectivity Beatrice Bravi; Marco Paolini; Federica Colombo; Mariagrazia Palladini; Valentina Bettonagli; Mario Gennaro Mazza; Rebecca De Lorenzo; Patrizia Rovere-Querini; Francesco Benedetti; Sara Poletti AIMS After 3 years from the...

Dynamic brain glymphatic changes and cognitive function in COVID-19 recovered patients: a DTI-ALPS prospective cohort study He, Chengcheng; Xie, Jinmei; Fang, Weiwei; Guo, Baoqin; Shi, Yangyang; Li, Anan; Liu, Hao; Zhu, Zhimin; Bao, Wenrui; Niu, Xuan; Wang, Shaoyu; Fu, Juan; Li, Hua; Xie...

Prevalence of Persistent Cardiovascular and Pulmonary Abnormalities on PET/MRI and DECT Imaging in Long COVID Patients Maria Giovanna Trivieri; Ana Devesa; Philip M. Robson; Sonali Bose; Busra Cangut; Steve Liao; Audrey Kaufman; Renata Pyzik; Valentin Fauveau; Jamie Wood; Aaron Shpiner; Edwin...

Reduced microstructural white matter integrity is associated with the severity of physical symptoms in functional neurological disorder Gninenko; Müller; Aybek BACKGROUND Functional neurological disorder (FND) is linked to functional changes in brain networks without an underlying brain lesion...

Neuroplastic changes in patients with functional seizures following neurobehavioral therapy Sharma; Allendorfer; Correia; Gaston; Goodman; Grayson; Philip; LaFrance; Szaflarski Given the high prevalence of functional neurological symptom disorder and its negative effects on the individual...

Towards whole brain mapping of the haemodynamic response function Fabio Mangini; Marta Moraschi; Daniele Mascali; Maria Guidi; Michela Fratini; Silvia Mangia; Mauro DiNuzzo; Fabrizio Frezza; Federico Giove Functional magnetic resonance imaging time-series are conventionally processed by linear...

Abnormal Coronary Vascular Response in Patients with Long COVID Syndrome – a Case-Control Study Using Oxygenation-Sensitive Cardiovascular Magnetic Resonance Weberling; Hillier; Friedrich; Zahlten; Frey; André; Steen BACKGROUND Following the world-wide COVID-19 pandemic, many patients reported...

Abstract Background/Objectives: Headache is one of the most common neurological symptoms associated with COVID-19, affecting approximately 25% of patients. While most headaches resolve within weeks, some persist for months, suggesting underlying structural brain changes. This study aimed to...

Reversible reduction in brain myelin content upon marathon running Ramos-Cabrer, Pedro; Cabrera-Zubizarreta, Alberto; Padro, Daniel; Matute-González, Mario; Rodríguez-Antigüedad, Alfredo; Matute, Carlos Here we use magnetic resonance imaging to study the impact of marathon running on brain...

Asymmetrical glymphatic dysfunction in patients with long Covid associated neurocognitive impairment- correlation with BBB disruption Chaganti, Joga R.; Talekar, Tanush K.; Brew, Bruce James BACKGROUND AND PURPOSE The glymphatic system, a waste clearance pathway, has been implicated in several...

Post-COVID microvascular dysfunction in hospitalized COVID-19 survivors is associated with acute disease severity and persistent cognitive complaints Noa van der Knaap; Simona Klinkhammer; Alida A. Postma; Johanna M.A. Visser-Meily; Janneke Horn; Caroline M. van Heugten; Paulien H.M. Voorter...

Imaging of Thromboinflammation by Multispectral 19F MRI Temme, Sebastian; Kleimann, Patricia; Tiren, Zeynep-Büsra; Bouvain, Pascal; Zielinski, Arthur; Dollmeyer, William; Poth, Sarah; Görges, Juliana; Flögel, Ulrich The close interplay between thrombotic and immunologic processes plays an...

Structural brain changes in post-COVID condition and its relationship with cognitive impairment Pacheco-Jaime, Laura et 52 al. It has been estimated that ~4% of individuals infected with SARS-CoV-2 will be diagnosed with post-COVID condition. Previous studies have evidenced the presence of...