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Full title: Efficacy and safety of rozanolixizumab in severe fibromyalgia: a phase 2A randomised, double-blind, placebo-controlled, multicentre trial Background Fibromyalgia is a chronic disorder characterised by widespread pain, fatigue, sleep disturbances, and cognitive dysfunction. Evidence...

Nirmatrelvir–ritonavir targeting viral persistence in post-COVID-19 condition long COVID in the USA RECOVER-VITAL: a randomised, double-blind, placebo-controlled, phase 2 trial Lindsey R Baden + 253 others BACKGROUND Post-acute sequelae of SARS-CoV-2 infection, more commonly known as long...

Symptom Response to Low-Dose Naltrexone in Fibromyalgia: An Exploratory Analysis of the Randomized Placebo-Controlled FINAL Trial Nielsen, Maria Juul; Vaegter, Henrik Bjarke; Bruun, Karin Due Abstract Background: Fibromyalgia (FM) remains difficult to manage due to a highly variable symptom...

Impact of immunoadsorption on autoantibodies and physical performance in post-COVID patients: a prospective exploratory study of 18 participants PURPOSE Autoantibodies against β-adrenergic and muscarinic acetylcholine receptors are said to play a role in the pathophysiology of post-COVID...

Feasibility and outcomes of crossflow membrane plasmapheresis for long COVID in Suriname: a randomized double-blind placebo-controlled pilot trial Background Long COVID is heterogeneous and currently without cure. The disease resembles myalgic encephalomyelitis/chronic fatigue syndrome...

Additional effects of group training and online exercise to a 12-week online pacing and education module on health-related quality of life in adult patients with post COVID-19: a randomized controlled trial Gartemann, Sophie; Luedtke, Kerstin Abstract This study assessed the effectiveness of a...

The Use of a Handheld Non-Invasive Vagal Nerve Stimulation nVNS Device for the Treatment of Long COVID: A Pilot Randomized Controlled Trial OBJECTIVES Long-term symptoms following infection with acute respiratory syndrome coronavirus-2 (SARS-CoV-2), termed post-acute sequelae of SARS-CoV-2...

Efficacy of a psychotherapeutic group intervention for patients with Post-COVID-19 condition: a randomized controlled trial (PsyLoCo study) Abstract Background Persistent physical symptoms such as fatigue following SARS-CoV-2 infection are common and often accompanied by cognitive complaints...

Efficacy and safety of rivaroxaban, colchicine, and famotidine–loratadine with specialist supportive clinical care for fatigue in patients with post-COVID-19 condition in the UK: a multisite, open-label, randomised controlled trial (STIMULATE-ICP consortium) Abstract: Background Post-acute...

Temelimab versus placebo in patients with post-COVID condition INTRODUCTION More than 400 million individuals are estimated to have been affected by post-COVID condition or long COVID. This condition can lead to significantly decreased quality of life and increased individual and societal...

Abstract Background Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a disabling condition withlimited treatment options and inadequate healthcare structures worldwide. We assessed the effectiveness of an integrated care model specifically adapted for ME/CFS. Methods In this...

Transcranial direct current stimulation in affecting neuropsychiatric symptoms of post-COVID syndrome: No change in microstates and functional connectivity INTRODUCTION Neuropsychiatric symptoms of post-covid syndrome (PCS) involve fatigue, brain fog, cognitive impairment, or symptoms of...

Spezialisierte kognitive Angebote bei Long-COVID-Symptomen nicht überlegen Hüll, Michael Abstract (Machine Translation) Question: Do cognitive training and rehabilitation strategies improve cognitive symptoms (such as memory problems, impaired concentration, “brain fog”) in Long COVID...

Immunoadsorption Versus Sham Treatment for Post-COVID Syndrome: A Randomised Sham-Controlled Crossover Trial BACKGROUND Post-Covid syndrome is a debilitating condition which may be caused and/or aggravated by autoantibodies. The current study aimed to determine whether autoantibody depletion...

Poster abstract from the EULAR rheumatology conference - EFFICACY OF LOW-DOSE NALTREXONE FOR FIBROMYALGIA: A RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL WITH 12 MONTHS OF FOLLOW-UP (Luciano et al., 2026) Low-Dose Naltrexone Fails to Outperform Placebo for Pain in Fibromyalgia Treatment...

Effect of Percutaneous Auricular Nerve Stimulation on Fatigue in Adults with Post-COVID Fatigue (PAuSing-pCF): Results of a Randomised, Sham-Controlled Trial Background Post-COVID fatigue (pCF) affects 2.3% of the UK population and causes physical and mental fatigue, impacting daily life...

Transcutaneous Auricular Vagal Nerve Stimulation Against Fatigue Syndrome in Patients with Long COVID: Results of the Randomized, Placebo-Controlled Clinical Pilot Trial COVIVA INTRODUCTION Fatigue is the most prevalent symptom in “long COVID”, affecting 6–7% of patients after COVID-19...

Feasibility and preliminary effects of a yoga program developed for adults with post COVID-19 condition Breathe Easy: pilot randomized controlled trial INTRODUCTION Effective medical management of post COVID-19 condition (post COVID) remains challenging. Symptoms are heterogenous...

The Effect of Fluvoxamine and Metformin for Fatigue in Patients With Long COVID Abstract Abstract Background and Objective: Postacute sequelae of SARS-CoV-2, or long COVID, presents a major therapeutic challenge, with fatigue being a prevalent and debilitating symptom. Objective: To assess...

Cognitive and Neuropsychiatric Sequelae After SARS-CoV-2 Infection: A Narrative Review and Exploratory Cross-Sectional Study of Neurofilament Light Chain and GFAP BACKGROUND Persistent cognitive and neuropsychiatric symptoms have been increasingly reported as part of the post-COVID-19...