Exploratory clinical and immunological changes following Tixagevimab/Cilgavimab administration in immunodeficient patients with SARS-CoV-2-associated ME/CFS and persistent circulating spike protein
Seidel; Anft; Wiemers; Seibert; Bertram; Rosiewicz; Stervbo; Westhoff; Babel
BACKGROUND...
Effectiveness of tailored individual follow-up vs. standard one-day group course on health-related quality of life in patients with post COVID-19 condition: a randomized controlled trial
Wilson, Marte; Michalsen, Henriette; Anke, Audny; Pedersen, Synne G; Espinasse, Marina; Langeland, Nina; Cox...
Effects of specialized pro-resolving mediators and telerehabilitation on fatigue, dyspnea, and quality of life in post‑COVID‑19 condition: the ARACOV-02 randomized controlled trial
Abstract
Background
Post‑COVID‑19 Condition (PCC) is characterized by persistent multisystem symptoms, with...
Immunoglobulin Replacement Does Not Correlate With Overall Improvement in Post-Acute Sequelae of COVID-19 Symptoms
Rationale
Immunoglobulin (Ig) replacement therapy is a current treatment for patients with certain immune deficiencies. Multiple pathophysiologic mechanisms have indicated the...
Faecal microbiota transplantation in irritable bowel syndrome (REFIT2): a randomised, double-blind, placebo-controlled, phase 3 trial
Abstract
Background
Gut microbiota composition might have a role in the pathogenesis of irritable bowel syndrome (IBS), and faecal microbiota transplantation...
Full title: Efficacy and safety of rozanolixizumab in severe fibromyalgia: a phase 2A randomised, double-blind, placebo-controlled, multicentre trial
Background
Fibromyalgia is a chronic disorder characterised by widespread pain, fatigue, sleep disturbances, and cognitive dysfunction. Evidence...
Nirmatrelvir–ritonavir targeting viral persistence in post-COVID-19 condition long COVID in the USA RECOVER-VITAL: a randomised, double-blind, placebo-controlled, phase 2 trial
Lindsey R Baden + 253 others
BACKGROUND
Post-acute sequelae of SARS-CoV-2 infection, more commonly known as long...
Symptom Response to Low-Dose Naltrexone in Fibromyalgia: An Exploratory Analysis of the Randomized Placebo-Controlled FINAL Trial
Nielsen, Maria Juul; Vaegter, Henrik Bjarke; Bruun, Karin Due
Abstract
Background: Fibromyalgia (FM) remains difficult to manage due to a highly variable symptom...
Impact of immunoadsorption on autoantibodies and physical performance in post-COVID patients: a prospective exploratory study of 18 participants
PURPOSE
Autoantibodies against β-adrenergic and muscarinic acetylcholine receptors are said to play a role in the pathophysiology of post-COVID...
Feasibility and outcomes of crossflow membrane plasmapheresis for long COVID in Suriname: a randomized double-blind placebo-controlled pilot trial
Background
Long COVID is heterogeneous and currently without cure. The disease resembles myalgic encephalomyelitis/chronic fatigue syndrome...
Additional effects of group training and online exercise to a 12-week online pacing and education module on health-related quality of life in adult patients with post COVID-19: a randomized controlled trial
Gartemann, Sophie; Luedtke, Kerstin
Abstract
This study assessed the effectiveness of a...
The Use of a Handheld Non-Invasive Vagal Nerve Stimulation nVNS Device for the Treatment of Long COVID: A Pilot Randomized Controlled Trial
OBJECTIVES
Long-term symptoms following infection with acute respiratory syndrome coronavirus-2 (SARS-CoV-2), termed post-acute sequelae of SARS-CoV-2...
Efficacy of a psychotherapeutic group intervention for patients with Post-COVID-19 condition: a randomized controlled trial (PsyLoCo study)
Abstract
Background
Persistent physical symptoms such as fatigue following SARS-CoV-2 infection are common and often accompanied by cognitive complaints...
Efficacy and safety of rivaroxaban, colchicine, and famotidine–loratadine with specialist supportive clinical care for fatigue in patients with post-COVID-19 condition in the UK: a multisite, open-label, randomised controlled trial (STIMULATE-ICP consortium)
Abstract:
Background
Post-acute...
Temelimab versus placebo in patients with post-COVID condition
INTRODUCTION
More than 400 million individuals are estimated to have been affected by post-COVID condition or long COVID. This condition can lead to significantly decreased quality of life and increased individual and societal...
Now published, see post #19.
Abstract
Background
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a disabling condition withlimited treatment options and inadequate healthcare structures worldwide. We assessed the effectiveness of an integrated care model specifically adapted for...
Transcranial direct current stimulation in affecting neuropsychiatric symptoms of post-COVID syndrome: No change in microstates and functional connectivity
INTRODUCTION
Neuropsychiatric symptoms of post-covid syndrome (PCS) involve fatigue, brain fog, cognitive impairment, or symptoms of...
Merged thread
Spezialisierte kognitive Angebote bei Long-COVID-Symptomen nicht überlegen
Hüll, Michael
Abstract (Machine Translation)
Question: Do cognitive training and rehabilitation strategies improve cognitive symptoms (such as memory problems, impaired concentration, “brain fog”) in...
Immunoadsorption Versus Sham Treatment for Post-COVID Syndrome: A Randomised Sham-Controlled Crossover Trial
BACKGROUND
Post-Covid syndrome is a debilitating condition which may be caused and/or aggravated by autoantibodies. The current study aimed to determine whether autoantibody depletion...
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