pots

Shared autonomic phenotype of long COVID and myalgic encephalomyelitis/chronic fatigue syndrome Peter Novak; David M Systrom; Alexandra Witte; Sadie P Marciano; Donna Felsenstein; Jeff M Milunsky; Aubrey Milunsky; Joel Krier; Mark C Fishman INTRODUCTION Long COVID and myalgic...

Impact of COVID‑19 infection on subsequent prescriptions of autonomic dysfunction pharmacotherapy: a nationwide propensity‑score‑matched Cohort study in Japan Daisuke Miyamori; Masanori Ito BACKGROUND Autonomic dysfunction, including orthostatic hypotension and postural tachycardia syndrome...

Key Points Question What is the prevalence of central sensitization syndrome in postural tachycardia syndrome (POTS)? Findings This case-control study of 305 patients found a high prevalence (86.5%) of central sensitization syndrome in individuals with POTS. Meaning These findings suggest...

Postural orthostatic tachycardia syndrome (POTS) is a complex disorder mainly of orthostatic intolerance, often accompanied by a spectrum of symptoms related to autonomic nervous system dysfunction. Although the diagnostic criteria require an orthostatic challenge test, the associated symptom...

Journal of Clinical Medicine: Special Issue Deadline for manuscript submissions: 20 January 2026 Special Issue Information Dear Colleagues, Postural orthostatic tachycardia syndrome (POTS), myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and long COVID are complex syndromes caused...

Desmopressin acutely decreases tachycardia and improves symptoms in the postural tachycardia syndrome Background Postural tachycardia syndrome (POTS) induces disabling chronic orthostatic intolerance with an excessive increase in heart rate on standing, and many patients...

Post-translational modifications within fibrinaloid microclot complexes distinguish Pre-COVID-19 Postural Orthostatic Tachycardia Syndrome (POTS), Long COVID, and Long COVID-POTS and reveal disease-specific molecular pathways Background: Pre-COVID-19 Postural orthostatic tachycardia syndrome...

Postural Orthostatic Tachycardia With Chronic Fatigue After HPV Vaccination as Part of the “Autoimmune/Auto-inflammatory Syndrome Induced by Adjuvants” Abstract We report the case of a 14-year-old girl who developed postural orthostatic tachycardia syndrome (POTS) with chronic fatigue 2...

Effect of subcutaneous lidocaine–hydroxypropyl-β-cyclodextrin (HP-β-CD) on quality of life in patients with post-COVID condition: a 36-week observational interrupted time series study Summary Background Post-COVID involves persistent, multisystem symptoms which are associated with...

Background: Orthostatic intolerance syndromes such as Orthostatic Hypotension (OH) and Postural Orthostatic Tachycardia Syndrome (PoTS) are common symptoms seen in post-infection conditions and other neurological conditions with autonomic dysfunction. The 10-min Lean Test (LT) is an objective...

Ivabradine as a treatment for postural orthostatic tachycardia syndrome: A systematic review Abstract Ivabradine is one of several off-label treatments for patients with postural orthostatic tachycardia syndrome (POTS). We conducted a systematic review of the literature to identify studies...

Central arterial stiffness, flow-mediated dilation and venous function in postural orthostatic tachycardia syndrome POTS Postural Orthostatic Tachycardia Syndrome (POTS) is a debilitating disorder characterised by excessive increases in heart rate upon standing and poor orthostatic tolerance...

Abstract Background Cardiovascular autonomic disorders (CAD) were described following COVID-19 infection and vaccination, but previous reports were limited in size and follow-up. Here, we aimed to investigate the type and frequency of newly diagnosed and exacerbated CAD following COVID-19...

https://link.springer.com/article/10.1007/s10286-025-01172-2 Systematic literature review: treatment of postural orthostatic tachycardia syndrome (POTS) Review Article Open access Published: 12 November 2025 (2025) Nicole Schiweck, Katharina Langer, Andrea Maier, Daniel Vilser & Juliane...

Abstract Purpose Despite the central role of exercise in treating postural orthostatic tachycardia syndrome (POTS) there have been no studies on the subjective experience of exercise interventions and/or recommendations among this patient population. The purpose of this mixed-methods study was...

Evaluating the risk and risk factors of dysautonomia as a post-acute sequelae of COVID-19: a secondary analysis of a matched case–control dataset BACKGROUND A significant proportion of patients presenting with post-acute sequelae of COVID-19 (PASC) have been found to meet diagnostic criteria...

Water drinking as a treatment for orthostatic syndromes John R Shannon, Andre Diedrich, Italo Biaggioni, Jens Tank, Rose Marie Robertson, David Robertson, Jens Jordan Abstract Purpose: Water drinking increases blood pressure in a substantial proportion of patients who have severe...

Time-restricted eating improves quality of life, heart rate, and mitochondrial function in patients with postural orthostatic tachycardia syndrome. An open-label pilot study Postural orthostatic tachycardia syndrome (POTS) is characterized by an abnormal increase in heart rate upon standing...

Prevalence and Clinical Impact of Postural Orthostatic Tachycardia Syndrome in Highly Symptomatic Long COVID BACKGROUND The incidence of postural orthostatic tachycardia syndrome (POTS) in long COVID has been a growing concern since the first cases were reported in 2021. The aim of this study...

Abstract Background/Objectives: Symptoms of autonomic dysfunction are common in infection-associated chronic conditions and illnesses (IACCIs), including myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). This study aimed to evaluate autonomic symptoms and their impact on ME/CFS...