An abstarct was presented during the American College of Cardiology's 75th Annual Scientific Session & Expo, 28-30 March 2026
BACKGROUND Patients with postural orthostatic tachycardia syndrome (POTS) exhibit unique hemodynamics. Invasive cardiopulmonary exercise testing (iCPET) may provide...
Hives in autonomic disorders: a cutaneous marker of a distinct symptom phenotype
Abstract
Background
Postural Orthostatic Tachycardia Syndrome (POTS) and Neurally-Mediated Hypotension (NMH) are heterogeneous syndromes characterized by dysautonomia and multisystem symptoms.
Mast cell...
Disequilibrium, Rather than Postural Orthostatic Tachycardia Syndrome, Is the Primary Determinant of Orthostatic Intolerance in Patients with Long COVID
Miwa, Kunihisa
Background
Orthostatic intolerance (OI) is an important factor affecting daily functional capacity in patients with long...
Abstract
Background
Postural orthostatic tachycardia syndrome (POTS) is a chronic autonomic disorder associated with debilitating symptoms. No medications have been approved for treatment, and patients commonly use off-label medications to treat symptoms. The hemodynamic implications of certain...
Postural orthostatic tachycardia is not a useful diagnostic marker for chronic fatigue syndrome
M. E. Roerink, J. W. M. Lenders, I. C. Schmits, A. M. A. Pistorius, J. W. Smit, H. Knoop, J. W. M. van der Meer
First published: 02 October 2016
https://doi.org/10.1111/joim.12564
Abstract...
Shared autonomic phenotype of long COVID and myalgic encephalomyelitis/chronic fatigue syndrome
Peter Novak; David M Systrom; Alexandra Witte; Sadie P Marciano; Donna Felsenstein; Jeff M Milunsky; Aubrey Milunsky; Joel Krier; Mark C Fishman
INTRODUCTION
Long COVID and myalgic...
Impact of COVID‑19 infection on subsequent prescriptions of autonomic dysfunction pharmacotherapy: a nationwide propensity‑score‑matched Cohort study in Japan
Daisuke Miyamori; Masanori Ito
BACKGROUND
Autonomic dysfunction, including orthostatic hypotension and postural tachycardia syndrome...
Key Points
Question What is the prevalence of central sensitization syndrome in postural tachycardia syndrome (POTS)?
Findings This case-control study of 305 patients found a high prevalence (86.5%) of central sensitization syndrome in individuals with POTS.
Meaning These findings suggest...
Postural orthostatic tachycardia syndrome (POTS) is a complex disorder mainly of orthostatic intolerance, often accompanied by a spectrum of symptoms related to autonomic nervous system dysfunction. Although the diagnostic criteria require an orthostatic challenge test, the associated symptom...
Journal of Clinical Medicine: Special Issue
Deadline for manuscript submissions: 20 January 2026
Special Issue Information
Dear Colleagues,
Postural orthostatic tachycardia syndrome (POTS), myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and long COVID are complex syndromes caused...
Desmopressin acutely decreases tachycardia and improves symptoms in the postural tachycardia syndrome
Background
Postural tachycardia syndrome (POTS) induces disabling chronic orthostatic intolerance with an excessive increase in heart rate on standing, and many patients...
Postural Orthostatic Tachycardia With Chronic Fatigue After HPV Vaccination as Part of the “Autoimmune/Auto-inflammatory Syndrome Induced by Adjuvants”
Abstract
We report the case of a 14-year-old girl who developed postural orthostatic tachycardia syndrome (POTS) with chronic fatigue 2...
Effect of subcutaneous lidocaine–hydroxypropyl-β-cyclodextrin (HP-β-CD) on quality of life in patients with post-COVID condition: a 36-week observational interrupted time series study
Summary
Background
Post-COVID involves persistent, multisystem symptoms which are associated with...
Background: Orthostatic intolerance syndromes such as Orthostatic Hypotension (OH) and Postural Orthostatic Tachycardia Syndrome (PoTS) are common symptoms seen in post-infection conditions and other neurological conditions with autonomic dysfunction. The 10-min Lean Test (LT) is an objective...
Ivabradine as a treatment for postural orthostatic tachycardia syndrome: A systematic review
Abstract
Ivabradine is one of several off-label treatments for patients with postural orthostatic tachycardia syndrome (POTS). We conducted a systematic review of the literature to identify studies...
Central arterial stiffness, flow-mediated dilation and venous function in postural orthostatic tachycardia syndrome POTS
Postural Orthostatic Tachycardia Syndrome (POTS) is a debilitating disorder characterised by excessive increases in heart rate upon standing and poor orthostatic tolerance...
Abstract
Background
Cardiovascular autonomic disorders (CAD) were described following COVID-19 infection and vaccination, but previous reports were limited in size and follow-up. Here, we aimed to investigate the type and frequency of newly diagnosed and exacerbated CAD following COVID-19...
https://link.springer.com/article/10.1007/s10286-025-01172-2
Systematic literature review: treatment of postural orthostatic tachycardia syndrome (POTS)
Review Article
Open access
Published: 12 November 2025
(2025)
Nicole Schiweck,
Katharina Langer,
Andrea Maier,
Daniel Vilser &
Juliane...
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