pots

Title: Orthostatic intolerance and tachycardia associated with norepinephrine-transporter deficiency Authors: John R. Shannon, M.D., Nancy L. Flattem, B.S., Jens Jordan, M.D., Giris Jacob, M.D., D.Sc., Bonnie K. Black, B.S.N., Italo Biaggioni, M.D., Randy D. Blakely, Ph.D., and David Robertson...

Neurological, Neuromuscular, and Autonomic Manifestations of COVID-19: A Retrospective Study Abstract Background Neurovascular, neuromuscular, and autonomic complications of COVID-19 have rarely been characterized within a single cohort. Objective To compare the clinical, electrodiagnostic...

Increase in children with postural tachycardia syndrome after the COVID-19 pandemic Abstract Background The number of children diagnosed with orthostatic intolerance (OI) has been increasing. In adults, diagnoses of postural tachycardia syndrome (POTS), a type of OI, increased markedly after...

Orthostatic and exercise intolerance in post-acute sequelae of COVID-19 occur with intact sympathetic neural control and preserved cardiac reserve Erin J Howden; Gianni Sesa-Ashton; Stephen J Foulkes; Imogen Wallace; Leah Wright; Benedict Costello; Andre La Gerche; Vaughan G Macefield PURPOSE...

Targeting Brain-Body Processes in Postural Tachycardia Syndrome: A Pilot Trial of POts Reprocessing Therapy Abstract Purpose Postural tachycardia syndrome (POTS) is a chronic autonomic disorder characterized by orthostatic intolerance and frequently accompanied by a broad constellation of...

Effectiveness of individualized physical exercise in COVID-19-induced Postural Orthostatic Tachycardia Syndrome Svensson, Annie M.; Svensson-Raskh, Anna U.M.; Törnberg, Anna C.; Hallberg, Carl E.; Holmström, Linda; Fedorowski, Artur; Nygren-Bonnier, Malin C. Background Postural orthostatic...

Assessing the Role of Patient-Physician Sex Concordance on Diagnostic Accuracy in Primary Care: A Randomized Factorial Survey Experiment Abstract Background While the impact of patient-physician sex concordance on patient perceptions and outcomes has been studied, less is known about its...

Evidence for positive long- and short-term effects of vaccinations against COVID-19 in wearable sensor metrics Abstract Vaccines are among the most powerful tools to combat the COVID-19 pandemic. They are highly effective against infection and substantially reduce the risk of severe disease...

Design and rationale of RECOVER-AUTONOMIC: A randomized platform trial evaluating interventions for Long COVID postural orthostatic tachycardia syndrome Abstract Background: Post‑acute sequelae of SARS‑CoV‑2 infection (Long COVID) affect a substantial proportion of individuals, and among the...

Hypovolemia in Syncope and Orthostatic Intolerance Role of the Renin-Angiotensin System Giris Jacob, David Robertson, Rogelio Mosqueda-Garcia, Andrew C. Ertl, Rose Marie Robertson, Italo Biaggioni https://www.sciencedirect.com/science/article/abs/pii/S0002934397001332 Sci-Hub...

Methyldopa for hyperadrenergic postural orthostatic tachycardia syndrome: A case series of five patients Highlights • Patients with POTS & hyperadrenergic features felt better after methyldopa therapy. • These patients reported improved orthostatic symptoms and sleep after methyldopa therapy...

Total blood volume and red blood cell volume are not associated with orthostatic intolerance in adults with myalgic encephalomyelitis/chronic fatigue syndrome Orthostatic intolerance is common in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and may worsen daily functioning...

https://www.nationalgeographic.com/health/article/pots-long-covid-autoimmune 1400-word article. Why Do POTS and Long Covid Look So Much Like Autoimmune Disorders? Researchers are studying the curious connection between autoimmune diseases and conditions like POTS and long COVID—in the hopes...

https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2026.1836407/full ORIGINAL RESEARCH article Front. Pediatr., 01 September 2026 Sec. Pediatric Neurology Volume 14 - 2026 | https://doi.org/10.3389/fped.2026.1836407 Postural orthostatic tachycardia syndrome in adolescents...

https://www.telegraph.co.uk/news/2026/09/05/disability-became-cool/ Archived Link 3400-word article How having a disability became cool Young women, nicknamed ‘sickfluencers’, are turning chronic illness into a lifestyle trend and entrenching a culture of economic inactivity Poppy Coburn...

Excessive Hypocapnic Cerebral Vasoconstriction in Hypermobile Ehlers–Danlos Syndrome Assessed With Real‐Time Magnetic Resonance Imaging During Lower‐Body Negative Pressure Darius A Gerlach; Anja Bach; Laura de Boni; Fiona Fischer; Tatjana Barth; Alex Hoff; Jorge Manuel; Jens Jordan; Andrea...

Baroreflex sensitivity impairment in Long-COVID patients: a diagnostic tool for classifying the autonomic dysfunction spectrum BACKGROUND Long-COVID describes a variety of COVID-19 side effects lasting longer than three months. Among these side effects are cardiovascular alterations, such as...

Familial Chiari Malformation: Prevalence of Connective Tissue Disorders and Other Comorbidities Heukwa-Tefoung, Anne; Bui, Alicia; Gilmer, Holly BACKGROUND AND OBJECTIVES: Chiari malformation type 1 (CM-I) is frequently associated with connective tissue disorders (CTDs), particularly...

Frequency and characteristics of multi‐domain autonomic dysfunction in patients with spontaneous intracranial hypotension Abstract Objective We aimed to evaluate multi-domain autonomic function in patients with spontaneous intracranial hypotension (SIH) and investigate its association with...

When Sinus Tachycardia Becomes Too Much Abstract Background: Upright posture reduces venous return, stroke volume, and cardiac output (CO) while causing reflex sinus rate (heart rate) increase. Yet, in inappropriate sinus tachycardia (IST), postural tachycardia syndrome (POTS), and vasovagal...