serotonin

Assessing the effect of selective serotonin reuptake inhibitors in the prevention of post-acute sequelae of COVID-19 Hythem Sidky; Kristen A. Hansen; Andrew T. Girvin; Nathan Hotaling; Sam G. Michael; Ken Gersing; David K. Sahner BACKGROUND Post-acute sequelae of COVID-19 (PASC) produce...

Treatment of 95 post-Covid patients with SSRIs Rus, Carla P.; de Vries, Bert E. K.; de Vries, Ingmar E. J.; Nutma, Idelette; Kooij, J. J. Sandra After Covid-19 infection, 12.5% develops post-Covid-syndrome (PCS). Symptoms indicate numerous affected organ systems. After a year, chronic fatigue...

Sequential multi-omics analysis identifies clinical phenotypes and predictive biomarkers for long COVID Kaiming Wang; Mobin Khoramjoo; Karthik Srinivasan; Paul M.K. Gordon; Rupasri Mandal; Dana Jackson; Wendy Sligl; Maria B. Grant; Josef M. Penninger; Christoph H. Borchers; David S. Wishart...

https://onlinelibrary.wiley.com/doi/10.1111/all.15253 Letter, open access Cork study Serum was obtained from PASC patients (n = 20) at two time points (4–6 months following infection (T1) and 6–9 months following infection (T2)). All patients had been hospitalized for PCR-proven SARS-CoV-2...

Serotonin reduction in post-acute sequelae of viral infection Highlights Long COVID is associated with reduced circulating serotonin levels Serotonin depletion is driven by viral RNA-induced type I interferons (IFNs) IFNs reduce serotonin through diminished tryptophan uptake and...

Immunometabolic rewiring in long COVID patients with chronic headache Suan-Sin Foo, Weiqiang Chen, Kyle L Jung, Tamiris Azamor, Un Yung Choi, Pengfei Zhang, Suzy AA Comhair, Serpil C Erzurum, Lara Jehi, Jae U Jung Almost 20% of patients with COVID-19 experience long-term effects, known as...

Study finds first direct evidence of a link between low serotonin and depression From the Guardian, science correspondent: Link to the study: BRAIN SEROTONIN RELEASE IS REDUCED IN PATIENTS WITH DEPRESSION: A [11C]Cimbi-36 PET STUDY WITH A D-AMPHETAMINE CHALLENGE.

Joanna Moncrieff, Ruth E. Cooper, Tom Stockmann, Simone Amendola, Michael P. Hengartner & Mark A. Horowitz The serotonin hypothesis of depression is still influential. We aimed to synthesise and evaluate evidence on whether depression is associated with lowered serotonin concentration or...

Something I have now seen a number of times over the last few months is people who have just been diagnosed talking about how it has been confirmed with a 5HT test. It would seem the healthcare (NHS-based it seems, maybe all from similar or the same place?) involved states this to be some sort...

https://journals.sagepub.com/doi/full/10.1177/1178646920936279

Moderator note: Link to @forestglip's excellent summary of what is known, as of August 2026, about the prolactin response to a buspirone challenge in ME/CFS here See also a Google document where some members are compiling findings and ideas related to prolactin response here. ******** I...

This thread has been split from the main Stanford Community Symposium 2018 thread. Interesting presentation on metabolic traps focussing on tryptophan/kyneurenine. Serotonin And a very clear and strong message from Ron Davis that people should not experiment on themselves because he said...

Open access at https://www.researchgate.net/publication/322727729_Effects_of_anti-inflammatory_drugs_on_the_expression_of_tryptophan-metabolism_genes_by_human_macrophages