sickness behavior

  1. Yann04

    Sickness behaviour and depression: An updated model of peripheral-central immunity interactions, Turkheimer et al, 2023

    Abstract: Current research into mood disorders indicates that circulating immune mediators participating in the pathophysiology of chronic somatic disorders have potent influences on brain function. This paradigm has brought to the fore the use of anti-inflammatory therapies as adjunctive to...
  2. Yann04

    Review Cytokine, Sickness Behavior, and Depression, 2009, Dantzer

    Abstract: Sufficient evidence is now available to accept the concept that the brain recognizes cytokines as molecular signals of sickness. Clarifying the way the brain processes information generated by the innate immune system is accompanied by a progressive elucidation of the cellular and...
  3. Yann04

    Acute Infection: Metabolic Responses, Effects on Performance, Interaction with Exercise, and Myocarditis, Friman et Ilbäck, 1998

    Abstract: Acute infections are associated with multiple host responses that are triggered by cytokines and correlated to fever, malaise and anorexia. The purpose of this systemic acute phase host reaction („the acute phase response”) is to mobilize nutrients for the increased needs of the...
  4. forestglip

    Comparing acute sickness symptoms with ME/CFS

    I thought it might be worthwhile to have a discussion comparing and contrasting the symptoms of an acute infection (a week or two of flu, cold, staph, etc.) and ME/CFS. Viral persistence is often mentioned in discussions of mechanism theories. I personally think there's a good chance ME/CFS is...
  5. forestglip

    Lack of fever during acute infections

    I very rarely get sick, but when I do, I don't seem to get a fever. I haven't measured my temperature while sick since I was little, so I can't be sure, but I don't get any "hot" feeling. Even when I was sick for a month straight with something downright awful and my lymph node had me this close...
  6. forestglip

    A narrative review on the similarities and dissimilarities between [ME/CFS] and sickness behavior, 2013, Morris et al

    A narrative review on the similarities and dissimilarities between myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and sickness behavior Gerwyn Morris, George Anderson, Piotr Galecki, Michael Berk, Michael Maes Abstract It is of importance whether myalgic encephalomyelitis/chronic...
  7. Andy

    An airway-to-brain sensory pathway mediates influenza-induced sickness 2023 Bin et al

    Abstract Pathogen infection causes a stereotyped state of sickness that involves neuronally orchestrated behavioural and physiological changes1,2. On infection, immune cells release a ‘storm’ of cytokines and other mediators, many of which are detected by neurons3,4; yet, the responding neural...
  8. C

    Illness Behaviour - a multidisciplinary approach McHugh and Vallis (EDIT)1986

    This book represents the papers delivered at the international conference on Illness Behavior held in Toronto in 1985. It should not be considered out of date. It was reprinted in 2013 and so it must be assumed that it is still used either for teaching material or by practitioners. Illness...
  9. A

    Identification of a brainstem locus that inhibits tumour necrosis factor, 2020, Kressel et al

    From Twitter Paper from earlier this year
  10. Dolphin

    Interleukin-1beta, heat shock protein 90alpha, and hypocretin-1 in chronic fatigue (not CFS) (PhD thesis), 2020, Bardsen

    Via Dr. Marc-Alexander Fluks
  11. Dolphin

    Difficulties of living with an illness not considered a 'Disease': Focusing on the illness behavior of ME/CFS, 2020, Nojima

    This isn't biomedical research so I posted it here.
  12. Hoopoe

    Patients with ME/CFS and chronic pain report similar level of sickness behavior as individuals injected with bacterial endotoxin... 2019, Jonsjö et al

    https://www.sciencedirect.com/science/article/pii/S2666354619300298
  13. Sly Saint

    Sickness & behavior in ME/CFS (Chronic Fatigue Syndrome) - Jonsjö, Martin 2019 (Thesis)

    https://openarchive.ki.se/xmlui/handle/10616/46839 seems to be favouring ACT
  14. Andy

    Pain and fatigue in primary Sjögren’s syndrome, 2019, Omdal et al

    Thought this might be of interest. https://academic.oup.com/rheumatology/advance-article-abstract/doi/10.1093/rheumatology/kez027/5366191 Sci Hub, https://sci-hub.tw/https://academic.oup.com/rheumatology/advance-article-abstract/doi/10.1093/rheumatology/kez027/5366191
  15. Manganus

    Shakar & Shakar on Sickness Behavior, 2015

    How to explain the evolutionary advantages of Sickness Behavior. This article is from 2015. Maybe the scientific frontier has advanced since. Anyone knows? Anyway: I'm a bit impressed. :) Source: https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002276
  16. C

    "Abnormal illness behaviour" and the missing citations.

    You will, from time to time, have seen references to "abnormal illness behaviour" in connection with ME or CFS, and these will no doubt have cited the various papers by Mechanic on the subject of "illness behaviour". It seems that this is not quite the full story. There appears to be a lacuna...
  17. Woolie

    Sickness behaviour – useful concept or psycho-humbug?

    Sickness behaviour is a concept that's often referred to in relation to MECFS. I want to see what people think of it. Whether there's something in it, or whether its just a tool used by the mind-over-body crowd. Here's a rough intro to the concept: Sickness behaviour refers to the behavioural...
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