sleep

Obstructive sleep apnoea and quality of life in Ehlers-Danlos syndrome: A parallel cohort study Thomas Gaisl, Cecilia Giunta, Daniel J Bratton, Kate Sutherland, Christian Schlatzer, Noriane Sievi, Daniel Franzen, Peter A Cistulli, Marianne Rohrbach, Malcolm Kohler...

Prevalence of Obstructive Sleep Apnea in Joint Hypermobility Syndrome: A Systematic Review and Meta-Analysis Karim Sedky, Thomas Gaisl, David S. Bennett https://jcsm.aasm.org/doi/10.5664/jcsm.7636 (PDF available) ABSTRACT Study Objectives: Because of associated abnormalities affecting...

Genome-wide meta-analysis identifies genetic risk loci for mono- and polyneuropathies in 983 477 individuals Peripheral neuropathies are common neurological disorders affecting sensory, autonomic, and motor nerves, with an estimated prevalence exceeding 2% in the general population. Typical...

Fluid transport in the brain The brain harbors a unique ability to, figuratively speaking, shift its gears. During wakefulness, the brain is geared fully toward processing information and behaving, while homeostatic functions predominate during sleep. The blood-brain barrier establishes a...

Prospective Associations of Long COVID with Sleep Health Nearly 3 Years After SARS-CoV-2 Infection: A Statewide Representative Cohort Study STUDY OBJECTIVES While many adults with Long COVID experience sleep problems, the long-term relationship between Long COVID and sleep remains poorly...

Neurofluid circulation changes during a focused attention style of mindfulness meditation Neurofluids, including cerebrospinal fluid (CSF) and interstitial fluid, circulate through regulated central nervous system pathways to clear cerebral waste and support brain health, with elevated CSF...

Somatic arousal and sleepiness/fatigue among patients with sleep-disordered breathing Morris S. Gold, Tshering Amdo, Nadia Hasaneen and Avram R. Gold https://www.researchgate.net/publication/289535169_Somatic_arousal_and_sleepinessfatigue_among_patients_with_sleep-disordered_breathing Sci-Hub...

Fibromyalgia in obstructive sleep apnea-hypopnea syndrome: a systematic review and meta-analysis Jie He, Meifeng Chen, Na Huang, and Bo Wang https://pmc.ncbi.nlm.nih.gov/articles/PMC11144865/ Abstract Introduction: Fibromyalgia (FM) is a common condition in patients with obstructive sleep...

Feasibility of predicting next-day fatigue levels using heart rate variability and activity-sleep metrics in people with post-COVID fatigue [Line breaks added] Background Post-COVID fatigue (pCF) represents a significant burden for many individuals following SARS-CoV-2 infection. The...

Glymphatic clearance controls state-dependent changes in brain lactate concentration Brain lactate concentration is higher during wakefulness than in sleep. However, it is unknown why arousal is linked to an increase in brain lactate and why lactate declines within minutes of sleep. Here, we...

Abstract 4369416: Impact of Long COVID on Physical Activity and Sleep: a Matched Cohort Study using Wearable and EHR data From The All of Us Research Program [Line breaks added] Backround Long COVID (LC) is associated with negative health effects, but its impact on health behaviors such as...

American Heart Association Scientific Sessions 2025 Among adults with insomnia, those whose electronic health records indicated long-term melatonin use (12 months or more) had about a 90% higher chance of incident heart failure over 5 years compared with matched non-users (4.6% vs. 2.7%...

Attentional failures after sleep deprivation are locked to joint neurovascular, pupil and cerebrospinal fluid flow dynamics Sleep deprivation rapidly disrupts cognitive function and in the long term contributes to neurological disease. Why sleep deprivation has such profound effects on...

Long COVID: Lung Pathophysiology and its Relationship with Cognitive Dysfunction Post-acute sequelae of COVID-19 (Long COVID) includes physical and cognitive symptoms that can last long after acute infection. Links between lung pathophysiology and cognitive dysfunction in Long COVID remain...

Sleep Architecture and REM Sleep Without Atonia in Post-COVID-19 Insomnia STUDY OBJECTIVES Insomnia associated with COVID-19 infection is a common complaint in long-COVID. Studies to date have predominantly examined post-COVID-19 sleep disturbances with questionnaires. We aimed to investigate...

Marked decrease in sleepiness in patients with sleep apnea by etanercept, a tumor necrosis factor-alpha antagonist A N Vgontzas, E Zoumakis, H-M Lin, E O Bixler, G Trakada, G P Chrousos Abstract The proinflammatory cytokines, TNFalpha and IL-6, are elevated in obstructive sleep apnea (OSA) and...

Effect of obesity on the acute response to SARS-CoV-2 infection and development of post-acute sequelae of COVID-19 PASC in nonhuman primates Long-term adverse consequences of SARS-CoV-2 infection, termed “long COVID” or post-acute sequelae of COVID (PASC), are a major component of overall...

*This post is in the process of being updated. People have given me feedback that sharing the Bluesky/Twitter threads is not a preferred/accessible option, so I will try to convey the relevant info here (it will likely have to be spread across multiple threads focusing on sub-topics). This will...

Sleep need–dependent plasticity of a thalamic circuit promotes homeostatic recovery sleep Sang Soo Lee; Qiang Liu; Alexandra H. R. Cheng; Dong Won Kim; Daphne M. Boudreau; Anuradha Mehta; Mehmet F. Keles; Rafal Fejfer; Isabelle Palmer; Kristen H. Park; Heike Münzberg; Timothy D. Harris; Austin...

The Implications and Predictability of Sleep Reversal for People with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Machine Learning Approach Meghan P. Dietrich, Raam Pravin, Jacob Furst, Leonard A. Jason Background/Objectives: Impaired sleep is one of the core symptoms of myalgic...