Objective versus subjective excessive daytime sleepiness in OSA: Quantifying the impact of fatigue
Morris S Gold, Riccardo A Stoohs, Avram R Gold
https://www.sciencedirect.com/science/article/abs/pii/S1389945726001061
Background
In patients with obstructive sleep apnea (OSA), excessive daytime...
Sleep alters neurovascular and hydrodynamic coupling in the human brain
Sleep is essential for maintaining brain tissue homeostasis, which is facilitated by enhanced cerebrospinal fluid (CSF) solute transport. Infraslow (<0.1 Hz) vasomotion, CSF flow, and electrophysiological potential all...
Immune control of sleep pressure via interferon-γ in mice
Sleep pressure reflects the brains homeostatic need to sleep, but the mechanisms underlying its regulation remain poorly understood. In mice, a subset of cortical inhibitory neuronal nitric oxide synthase (nNOS) positive interneurons...
Obstructive sleep apnea is a common disorder in the population—a review on the epidemiology of sleep apnea
Karl A Franklin, Eva Lindberg
https://pmc.ncbi.nlm.nih.gov/articles/PMC4561280/ (PDF available)
Abstract
The prevalence of obstructive sleep apnea (OSA) defined at an apnea-hypopnea index...
Sleep-Disordered Breathing Among Women With Fibromyalgia Syndrome
Shah, Mansi A.; Feinberg, Stanford; Krishnan, Eswar
Background
In clinical practice, polysomnograms (“sleep studies”) are seldom ordered for patients with fibromyalgia, although sleep issues dominate the symptom complex. One...
Inspiratory airflow dynamics during sleep in veterans with Gulf War illness: A controlled study
Mohammad M. Amin, Zuzana Belisova, Sayeed Hossain, Morris S. Gold, Joan E. Broderick, Avram R. Gold...
Psychomotor Vigilance Test and Its Association With Daytime Sleepiness and Inflammation in Sleep Apnea: Clinical Implications
Yun Li, Alexandros Vgontzas, Ilia Kritikou, Julio Fernandez-Mendoza, Maria Basta, Slobodanka Pejovic, Jordan Gaines, Edward O Bixler...
Increased Flow Limitation During Sleep Is Associated With Increased Psychomotor Vigilance Task Lapses in Individuals With Suspected OSA
Eric Staykov, Dwayne L Mann, Brett Duce, Samu Kainulainen, Timo Leppänen, Juha Töyräs, Ali Azarbarzin, Thomas Georgeson, Scott A Sands, Philip I Terrill...
Sleep loss induces cholesterol-associated myelin dysfunction
The increasing prevalence of sleep deprivation poses a public health challenge in modern society. Manifestations of reduced alertness, such as slowed reaction times and increased errors, are well-documented behavioral indicators of...
Sleep-disordered Breathing and Hypotension
Christian Guilleminault, John L. Faul, Riccardo Stoohs
https://academic.oup.com/ajrccm/article-abstract/164/7/1242/8544647 (SciHub link)
Abstract
We investigated the presence of low blood pressure (BP) in 4,409 subjects referred for overnight...
Prospective Randomized Controlled Trial on the Efficacy of Continuous Positive Airway Pressure and Adaptive Servo-Ventilation in the Treatment of Chronic Complex Insomnia
Barry Krakow, Natalia D. McIver, Victor A. Ulibarri, Jessica Krakow, Ronald M. Schrader...
Obstructive sleep apnoea and quality of life in Ehlers-Danlos syndrome: A parallel cohort study
Thomas Gaisl, Cecilia Giunta, Daniel J Bratton, Kate Sutherland, Christian Schlatzer, Noriane Sievi, Daniel Franzen, Peter A Cistulli, Marianne Rohrbach, Malcolm Kohler...
Prevalence of Obstructive Sleep Apnea in Joint Hypermobility Syndrome: A Systematic Review and Meta-Analysis
Karim Sedky, Thomas Gaisl, David S. Bennett
https://jcsm.aasm.org/doi/10.5664/jcsm.7636 (PDF available)
ABSTRACT
Study Objectives: Because of associated abnormalities affecting...
Genome-wide meta-analysis identifies genetic risk loci for mono- and polyneuropathies in 983 477 individuals
Peripheral neuropathies are common neurological disorders affecting sensory, autonomic, and motor nerves, with an estimated prevalence exceeding 2% in the general population. Typical...
Fluid transport in the brain
The brain harbors a unique ability to, figuratively speaking, shift its gears. During wakefulness, the brain is geared fully toward processing information and behaving, while homeostatic functions predominate during sleep. The blood-brain barrier establishes a...
Prospective Associations of Long COVID with Sleep Health Nearly 3 Years After SARS-CoV-2 Infection: A Statewide Representative Cohort Study
STUDY OBJECTIVES
While many adults with Long COVID experience sleep problems, the long-term relationship between Long COVID and sleep remains poorly...
Neurofluid circulation changes during a focused attention style of mindfulness meditation
Neurofluids, including cerebrospinal fluid (CSF) and interstitial fluid, circulate through regulated central nervous system pathways to clear cerebral waste and support brain health, with elevated CSF...
Somatic arousal and sleepiness/fatigue among patients with sleep-disordered breathing
Morris S. Gold, Tshering Amdo, Nadia Hasaneen and Avram R. Gold
https://www.researchgate.net/publication/289535169_Somatic_arousal_and_sleepinessfatigue_among_patients_with_sleep-disordered_breathing
Sci-Hub...
Fibromyalgia in obstructive sleep apnea-hypopnea syndrome: a systematic review and meta-analysis
Jie He, Meifeng Chen, Na Huang, and Bo Wang
https://pmc.ncbi.nlm.nih.gov/articles/PMC11144865/
Abstract
Introduction: Fibromyalgia (FM) is a common condition in patients with obstructive sleep...
Feasibility of predicting next-day fatigue levels using heart rate variability and activity-sleep metrics in people with post-COVID fatigue
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Background
Post-COVID fatigue (pCF) represents a significant burden for many individuals following SARS-CoV-2 infection. The...
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