Circulating Metabolome and White Matter Hyperintensities in Women and Men
Eeva Sliz; Jean Shin; Shahzad Ahmad; Dylan M. Williams; Stefan Frenzel; Friederike Gauß; Sarah E. Harris; Ann-Kristin Henning; Maria Valdes Hernandez; Yi-Han Hu; Beatriz Jiménez; Muralidharan Sargurupremraj; Carole Sudre...
Full Title: Dysregulations in hemostasis, metabolism, immune response, and angiogenesis in post-acute COVID-19 with and without POTS syndrome; a multi-omic profiling study, 2023, Ali Mahdi et al
Abstract
Post-acute COVID-19 (PACS) are associated with cardiovascular dysfunction, especially...
Significance
Chronic fatigue syndrome is a multisystem disease that causes long-term pain and disability. It is difficult to diagnose because of its protean symptoms and the lack of a diagnostic laboratory test. We report that targeted, broad-spectrum metabolomics of plasma not only revealed a...
Cancer-related cognitive impairment (CRCI) is a major neurotoxicity affecting more than 50% of cancer survivors. The underpinning mechanisms are mostly unknown, and there are no FDA-approved interventions. Sphingolipidomic analysis of mouse prefrontal cortex and hippocampus, key sites of...
Fereshteh Jahanbani, Rajan D. Maynard, Justin Cyril Sing, Shaghayegh Jahanbani, John J. Perrino, Damek V. Spacek, Ronald W. Davis, Michael P. Snyder
Received: January 17, 2022; Accepted: July 25, 2022; Published: August 9, 2022
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Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is...
electron microscopy
immune dysfunction
lipid droplets
lipid metabolism
lipids
mitochondria
mitochondrial architecture
omf
open medicine foundation
ron davis
smpd1
sphingolipids
t cells
Threads for the preprint and final paper have ben merged. Abstract for the final paper here.
PREPRINT
Evidence for Peroxisomal Dysfunction and Dysregulation of the CDP-Choline Pathway in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Xiaoyu Che, Christopher R Brydges, Yuanzhi Yu, Adam...
This is the latest work of Dr Naviaux and colleagues on cell-danger response, on mice.
Metabolic and behavioral features of acute hyperpurinergia and the maternal immune activation mouse model of autism spectrum disorder
Abstract
Since 2012, studies in mice, rats, and humans have suggested...
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