Extracellular vesicles promote autophagy in human microglia through lipid raft-dependent mechanisms
Diana Romenskaja; Ugne Jonavice; Augustas Pivoriunas
Autophagy dysfunction has been closely related with pathogenesis of many neurodegenerative diseases and therefore represents a potential...
Respiratory syncytial virus directly binds miR-26, miR-27, and let-7 to de-repress gene targets through canonical and non-canonical mechanisms
Sarah Ressel; Sujai Kumar; Jose Roberto Bermudez-Barrientos; Katrina Gordon; Julia Lane; Jin Wu; Cei Abreu-Goodger; Jurgen Schwarze; Amy H Buck
Specific...
Cancer-related cognitive impairment (CRCI) is a major neurotoxicity affecting more than 50% of cancer survivors. The underpinning mechanisms are mostly unknown, and there are no FDA-approved interventions. Sphingolipidomic analysis of mouse prefrontal cortex and hippocampus, key sites of...
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