The Use of a Handheld Non-Invasive Vagal Nerve Stimulation nVNS Device for the Treatment of Long COVID: A Pilot Randomized Controlled Trial
OBJECTIVES
Long-term symptoms following infection with acute respiratory syndrome coronavirus-2 (SARS-CoV-2), termed post-acute sequelae of SARS-CoV-2...
Vagal cholinergic denervation of the gastric mucosa in Long-COVID-19: in vivo evidence of structural autonomic dysfunction
Highlights
• Last evidences support autonomic dysfunction in the pathophysiology of Long COVID-19.
• In the gastrointestinal tract vagal innervation plays a role in the...
Transcutaneous Auricular Vagus Nerve Stimulation for Post-COVID-19 Condition: A Systematic Review and Critical Appraisal of Clinical Evidence
BACKGROUND
Long COVID, or post-COVID-19 condition (PCC), affects around 36% of individuals following SARS-CoV-2 infection, manifesting as persistent...
Percutaneous Auricular Nerve Stimulation for Treating Post-COVID Fatigue (PAuSing-pCF)
[Line breaks added]
Abstract
Even mild SARS-CoV-2 infection can lead to post-COVID syndrome, 70% of such patients have post-COVID fatigue (pCF).
Many physiological abnormalities observed in pCF could be...
Abstract
The inflammatory reflex, in which vagus nerve signaling modulates cytokine production, is dysregulated in rheumatoid arthritis (RA). RESET-RA, a pivotal, double-blind, randomized, sham-controlled trial, evaluated a vagus nerve-targeted neuromodulation system for RA in 242 patients with...
Survivor Corps is advocating with you to better understand COVID-19 and Long COVID through citizen science, research, legislation and policy.
Calling All Citizen Scientists!
Join a 4-week Study Exploring Wellness Products for Long COVID Symptoms. Join ASAP!
We’re inviting individuals with...
The device stimulates the vagus nerve, signaling the body to tamp down the inflammation that contributes to the disease.
https://www.nytimes.com/2025/07/31/health/arthritis-implant-vagus-setpoint.html?unlocked_article_code=1.a08.3D5y.AFO3sON3W_2K&smid=nytcore-ios-share&referringSource=articleShare
ABSTRACT
Background
Postural orthostatic tachycardia syndrome (POTS) is characterized by symptoms of orthostatic intolerance and is frequently observed in post-COVID conditions.
Objectives
We conducted controlled, prospective, and randomized clinical trials to explore the potential therapeutic...
Treatment with the SetPoint System, a neuroimmune modulation device, was associated with significant clinical benefit in adults with moderate to severe rheumatoid arthritis (RA), according to topline results from a phase 3 study.
The SetPoint System is a rechargeable neurostimulation device...
Noninvasive Vagus Nerve Stimulation in Postural Tachycardia Syndrome: A Randomized Clinical Trial
Stavros Stavrakis et al
"Abstract
Background
Low-level transcutaneous stimulation of the auricular branch of the vagus nerve at the tragus is antiarrhythmic and anti-inflammatory in animals and...
ABSTRACT
Background and objectives: Myalgic encephalomyelitis (ME) is a complex, multi-system neurological condition. Dysfunction of the autonomic nervous system is a primary feature in diagnostic criteria, and management may include attempts to stimulate the parasympathetic nervous system...
Vagus Nerve Dysfunction in the Post-COVID-19 Condition: a pilot cross sectional study
Abstract
Objective
The post-COVID-19 condition (PCC) is a disabling syndrome affecting at least 5-10% of subjects who survive COVID-19. SARS-CoV-2 mediated vagus nerve dysfunction could explain some PCC...
Researchers discover a potential cause of Parkinson’s disease | University of Helsinki
“Our findings are significant, as the cause of Parkinson’s disease has gone unknown despite attempts to identify it throughout the last two centuries. The findings indicate that specific strains of...
Effect of transcutaneous auricular vagal nerve stimulation on the fatigue syndrome in patients with gastrointestinal cancers — FATIVA: a randomized, placebo-controlled pilot study protocol
Abstract
Background
Cancer-related fatigue (CRF) is defined as a “distressing, persistent, subjective...
Background
Recent studies have demonstrated that antiadrenergic autoantibodies are involved in the pathophysiology of postural orthostatic tachycardia syndrome (POTS).
Objective
The purpose of this study was to test the hypothesis that transcutaneous low-level tragus stimulation (LLTS)...
Importance: Vagus nerve innervation via electrical stimulation and meditative-based diaphragmatic breathing may be promising treatment avenues for fibromyalgia.
Objective: Explore and compare the treatment effectiveness of active and sham transcutaneous vagus nerve stimulation (tVNS) and...
Trans-auricular vagus nerve stimulation to reduce perioperative pain and morbidity: protocol for a single-blind analyser-masked randomised controlled trial
Amour B.U. Patel, Phillip P.W.M. Bibawy, Zehra Majeed, Weng Liang Gan, Gareth L. Ackland
Background
Established or acquired loss of...
This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
By continuing to use this site, you are consenting to our use of cookies.