viral persistence

  1. J

    Preprint Relationship between acute SARS-CoV-2 viral clearance with Long COVID Symptoms: a cohort study, 2024, Herbert et al

    Abstract Introduction: The relationship between SARS-CoV-2 viral dynamics during acute infection and the development of long COVID is largely unknown. Methods: A total of 7361 asymptomatic community-dwelling people enrolled in the Test Us at Home parent study between October 2021 and February...
  2. SNT Gatchaman

    Trial Report Assessment of the Impact of RNase in Patients With Severe Fatigue Related to Post-Acute Sequelae of SARS-CoV-2 Infection PASC, 2024, Andrews et al.

    Assessment of the Impact of RNase in Patients With Severe Fatigue Related to Post-Acute Sequelae of SARS-CoV-2 Infection PASC: A Randomized Phase 2 Trial of RSLV-132 Andrews, James S; Boonyaratanakornkit, Jim B; Krusinska, Eva; Allen, Suzanne; Posada, James A BACKGROUND Severe acute respiratory...
  3. Yann04

    USA Long Covid Action Project

    Hi I wanted to create a thread on the organisation long covid action project to keep up with what they are doing. (A lot of which worries me.) This organisation says and claims as fact that long covid is a single disease caused by viral persistance. From their front page: Long Covid is a...
  4. SNT Gatchaman

    Clearance of gut mucosal SARS-CoV-2 antigens and post-acute COVID-19 after two years in patients with inflammatory bowel disease, 2024, Zollner et al.

    Clearance of gut mucosal SARS-CoV-2 antigens and post-acute COVID-19 after two years in patients with inflammatory bowel disease Andreas Zollner; Robert Koch; Almina Jukic; Alexandra Pfister; Moritz Meyer; Nikolaus Wick; Georg Wick; Annika Rössler; Janine Kimpel; Timon E. Adolph; Herbert Tilg...
  5. Mij

    The silent reservoir? SARS-CoV-2 detection in the middle ear effusion of pts with Otitis media with effusion after omicron infection, 2024, C Han

    Abstract Purpose This multicenter, prospective study is designed to investigate whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is present in the Middle Ear Effusion (MEE) of patients developing Otitis Media with Effusion (OME) subsequent to an Omicron infection. The...
  6. SNT Gatchaman

    Preprint Restrained memory CD8+ T cell responses favors viral persistence and elevated IgG responses in patients with severe Long COVID., 2024, Rodriguez et al

    Restrained memory CD8+ T cell responses favors viral persistence and elevated IgG responses in patients with severe Long COVID. Lucie Rodriguez; Ziyang Tan; Lakshmi Kanth Tadepally; Jun Wang; Hugo Barcenilla; Zoe Swank; Fanglei Zuo; Hassan Abolhassani; Ana Jimena Pavlovitch-Bedzyk; Chunlin Wang...
  7. LarsSG

    Blood transcriptomics reveal persistent SARS-CoV-2 RNA and candidate biomarkers in Long COVID patients, 2024, Menezes et al.

    Published as a preprint. See post #7 And now published in final form - link here ****** This is an abstract from the Demystifying Long COVID International Conference 2023, converted from an image on Twitter, so it might be slightly wonky, but it looks intriguing. Blood Transcriptomics Reveal...
  8. SNT Gatchaman

    Review The neurobiology of SARS-CoV-2 infection, 2023, Meinhardt et al.

    The neurobiology of SARS-CoV-2 infection Meinhardt, Jenny; Streit, Simon; Dittmayer, Carsten; Manitius, Regina v.; Radbruch, Helena; Heppner, Frank L. Worldwide, over 694 million people have been infected with SARS-CoV-2, with an estimated 55–60% of those infected developing COVID-19. Since the...
  9. E

    SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells, 2023, Huot et al

    SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA generally becomes undetectable in upper airways after a few days or weeks postinfection. Here we used a model of viral...
  10. SNT Gatchaman

    SARS-CoV-2 spike antigen-specific B cell and antibody responses in convalescent males and females with or without post-covid condition, 2023, Limoges+

    SARS-CoV-2 spike antigen-specific B cell and antibody responses in pre-vaccination period COVID-19 convalescent males and females with or without post-covid condition Limoges, Marc-André; Quenum, Akouavi Julite Irmine; Chowdhury, Mohammad Mobarak Hussain; Rexhepi, Fjolla; Namvarpour, Mozhdeh...
  11. E

    SARS-CoV-2 infection triggers pro-atherogenic inflammatory responses in human coronary vessels, 2023, Giannarelli et al

    SARS-CoV-2 infection triggers pro-atherogenic inflammatory responses in human coronary vessels Abstract Patients with coronavirus disease 2019 (COVID-19) present increased risk for ischemic cardiovascular complications up to 1 year after infection. Although the systemic inflammatory response to...
  12. E

    Tonsils are major sites of persistence of SARS-CoV-2 in children, 2023, Arruda et al

    Tonsils are major sites of persistence of SARS-CoV-2 in children ABSTRACT In the present study, we show that SARS-CoV-2 can infect palatine tonsils, adenoids, and secretions in children without symptoms of COVID-19, with no history of recent upper airway infection. We studied 48 children...
  13. Mij

    Two coronaviruses isolated from central nervous system tissue of two multiple sclerosis patients

    Abstract Two coronaviruses were isolated from brain material obtained at autopsy from two multiple sclerosis patients. The viruses were neutralized by serum and spinal fluid from these patients. Although most of the population have antibody to these virus isolates, multiple sclerosis patients...
  14. E

    Review SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC), 2023, Proal et al

    SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC) Abstract Millions of people are suffering from Long COVID or post-acute sequelae of COVID-19 (PASC). Several biological factors have emerged as potential drivers of PASC pathology. Some individuals with PASC may not fully clear the...
  15. SNT Gatchaman

    Trial Report A multicenter virome analysis of blood, feces, and saliva in myalgic encephalomyelitis/chronic fatigue syndrome, 2023, Briese et al.

    A multicenter virome analysis of blood, feces, and saliva in myalgic encephalomyelitis/chronic fatigue syndrome Thomas Briese; Rafal Tokarz; Lucinda Bateman; Xiaoyu Che; Cheng Guo; Komal Jain; Vishal Kapoor; Susan Levine; Mady Hornig; Alexandra Oleynik; Phenix-Lan Quan; Wai H. Wong; Brent L...
  16. SNT Gatchaman

    Multimodal Molecular Imaging Reveals Tissue-Based T Cell Activation and Viral RNA Persistence for Up to Two Years Following COVID-19, 2023, Peluso +

    Now published - link here ****** Preprint Multimodal Molecular Imaging Reveals Tissue-Based T Cell Activation and Viral RNA Persistence for Up to Two Years Following COVID-19 Michael J Peluso; Dylan M Ryder; Robert Flavell; Yingbing Wang; Jelena Levi; Brian H LaFranchi; Tyler-Marie M Deveau...
  17. E

    Long-Term Dysfunction of Taste Papillae in SARS-CoV-2, 2023 , Egan et al

    Long-Term Dysfunction of Taste Papillae in SARS-CoV-2 BACKGROUND We sought to determine whether ongoing taste disturbance in the postacute sequelae of coronavirus disease 2019 period is associated with persistent virus in primary taste tissue. METHODS We performed fungiform papillae biopsies...
  18. Hutan

    IIMEC 2023: Maureen Hanson

    IIMEC15 08 Professor Maureen Hanson 15th Invest in ME Research International ME Conference 2023 29 minutes Terrific presentation from Professor Maureen Hanson including some unpublished work I think we are getting close to some real answers - exhausted t-cells, abnormal classical monocytes...
  19. Hutan

    Advances in Model Systems for Human Cytomegalovirus Latency and Reactivation, 2022, Crawford et al

    Lindsey B. Crawford, a ,* Nicole L. Diggins, a Patrizia Caposio, a and Meaghan H. Hancock a Abstract Human cytomegalovirus (HCMV) is a highly prevalent beta-herpesvirus and a significant cause of morbidity and mortality following hematopoietic and solid organ transplant, as well as the leading...
  20. T

    (BMJ) "Where do viruses hide in the human body?", 2023, Extance

    https://www.bmj.com/content/382/bmj.p1156 Feature Covid Unanswered Questions Where do viruses hide in the human body? BMJ 2023; 382 doi: https://doi.org/10.1136/bmj.p1156 (Published 04 July 2023)Cite this as: BMJ 2023;382:p1156 Andy Extance, freelance journalist The question of how...
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