A genetic polymorphism that is associated with mitochondrial energy metabolism increases risk of fibromyalgia (2020) van Tilburg et al.

The prevalence of m.2352T>C is about 1% according to dbSNP
https://www.ncbi.nlm.nih.gov/snp/rs28358579

The PI on Twitter responded to a question about prevalence of this variant in FM. A bit hard to interpret, but maybe others figure it out.
https://twitter.com/user/status/1284653262873001985


Hopefully the paper will be available on sci-hub at some point.

 

Alan Light is carrying out a study looking at mtDNA in ME/CFS and FM. Be interesting to see if his data will also show relevance for this variant. This is his study
https://projectreporter.nih.gov/project_info_description.cfm?aid=9600713&icde=50901070

Thread with about a presentation of early data of his study here
https://www.s4me.info/threads/lives...ations-create-susceptibility-for-me-cfs.7072/

Video Presentation here :

 

m.2352T>C (rs28358579) has a consequence for gene MT-ND1. This is what Alan Light reported in the 2018 presentation about MT-ND1.

 

Weird how this science thing works differently when you follow the evidence where it leads you, instead of grabbing the evidence by the neck and forcing it your way.

https://twitter.com/user/status/1284917431669010434

 

She is demonstrating exactly what I believe: that the idea of psychosomatic illness is a false explanation that is preventing the discovery of the real causes of many illnesses. To make progress, these ideas need to be questioned first.