Review Cardiovascular effects of the post-COVID-19 condition, 2024, Goerlich et al.

SNT Gatchaman

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Cardiovascular effects of the post-COVID-19 condition
Goerlich, Erin; Chung, Tae H.; Hong, Gloria H.; Metkus, Thomas S.; Gilotra, Nisha A.; Post, Wendy S.; Hays, Allison G.

Throughout the COVID-19 pandemic, the new clinical entity of the postCOVID-19 condition, defined as a multisystemic condition of persistent symptoms following resolution of an acute severe acute respiratory syndrome coronavirus 2 infection, has emerged as an important area of clinical focus. While this syndrome spans multiple organ systems, cardiovascular complications are often the most prominent features. These include, but are not limited to, myocardial injury, heart failure, arrhythmias, vascular injury/thrombosis and dysautonomia. As the number of individuals with the post-COVID-19 condition continues to climb and overwhelm medical systems, summarizing existing information and knowledge gaps in the complex cardiovascular effects of the post COVID-19 condition has become critical for patient care.

In this Review, we explore the current state of knowledge of the post-COVID-19 condition and identify areas where additional research is warranted. This will provide a framework for better understanding the cardiovascular manifestations of the post-COVID-19 condition with a focus on pathophysiology, diagnosis and management.

Link | PDF (Nature Cardiovascular Research)
 
Unfortunately, there are no curative therapies for the post-COVID-19 condition; however, there are some effective therapies for subsets of patients especially targeted toward those with ME/CFS, which have been reviewed recently and are beyond the scope of the current review. An important concept in this population is that exercise is not recommended, with conflicting results in early studies and one study suggesting harm with exercise therapy to treat fatigue and related symptoms in the post-COVID-19 condition.
 
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