I would have thought so, just because the word conjures up images of 19th century tintypes of women splayed on fainting couches - but it turns out that it was mainly men who were diagnosed with neurasthenia, which was thought be a consequence of the fast-paced, energy-sapping qualities of American urban life in the second half of the 1800's.
This 2016 article in The Atlantic is quite hilarious in relating how non-specific the diagnosis was. It makes the late-1980's notion that neurasthenia was synonymous with Chronic Fatigue Syndrome seem ridiculous, simply because neurasthenia was apparently synonymous with nearly everything, including physical diseases and forms of mental illness that had not yet been distinguished.
For some "modern" researchers to proclaim that, "Oh yes, we've seen CFS before, back when it was called neurasthenia," is just ludicrous, as the 19th century diagnosis would have captured just about everyone whose illness was not recognized back then.