I guess every clnical trial starts with one patient, then more are added as suitable ones become available and agree to participate.Also, apparently, the first UK subject has entered a randomised treatment trial - I'm no scientist but I think we may need more than one subject for that kind of trial to work.
Yes, it will be particularly useful if they’re randomised to the placebo control arm of the trial.Also, apparently, the first UK subject has entered a randomised treatment trial - I'm no scientist but I think we may need more than one subject for that kind of trial to work.
ETA: He definitely said "turning the tide of", he may not have said "beating".
Obviously it’s dependent on social distancing. But is there a rough estimate
Just read this article in the Guardian, would like to see the data of their experiment.The author calls this "the Apollo challenge of our time".
Basically, a massive if expansion of testing and contact tracing (presumably after a massive short term lockdown to be clear on who isn't infected). And also massive antibody testing to establish who has already been infected and so can get back to work to keep the economy and society moving
Code:https://youtu.be/ORk0I2o0WPU
Do we know when we may be expected to “peak” and when it may be, that cases would come down to very low levels again, in the UK?
Obviously it’s dependent on social distancing. But is there a rough estimate
Seems to, yes.Did he say ‘hydroxyquinoline’?
Possibly/probably.Did he mean ‘hydroxychloroquin’?
I wouldn't know. I thought he seemed pretty angry to be honest.Sleep deprived?
Depends on whose rough estimate you want I guess!
The computer modellers will no doubt have an estimate with no relation to reality. The government may think they have a plan and an idea of how things will start to turn but from what I have seen they have no understanding at present.
My understanding of the situation is that it is currently driven by the fact that the NHS is now unable to cope but it will take another four or five days for that to become so apparent that complete lockdown in London will be inevitable. Maybe medical staff will walk out (mostly on an individual basis I suspect) when they see one or two more news items on their colleagues in Italy.
If things are locked down the current peak will start to go down in about ten days I think. By that time a bit more sense may prevail and it may go on going down. As to what happens next I have no idea but if the government relaxes things again too soon we will be back to where we are now pretty sharpish - within a month at most.
I am pretty sure that fairly soon what happens in the UK will just be dictated by the experience in Italy and also France, Spain and Germany. It should have done a month ago. So Whitty and Vallance will become irrelevances.
"New data has revealed that the United Kingdom has one of the highest coronavirus death rates in the world" ...
https://www.euronews.com/2020/03/19...d-19-death-rate-in-europe-on-a-par-with-china
A 4% death rate amongst confirmed cases.
Presumably there are various possible reasons for that. The obvious ones can think of:
- Fewer people being identified with the virus.
- Older demographic?
"New data has revealed that the United Kingdom has one of the highest coronavirus death rates in the world" ...
https://www.euronews.com/2020/03/19...d-19-death-rate-in-europe-on-a-par-with-china
A 4% death rate amongst confirmed cases.
Presumably there are various possible reasons for that. The obvious ones can think of:
- Fewer people being identified with the virus.
- Older demographic?
Depends on whose rough estimate you want I guess!
The computer modellers will no doubt have an estimate with no relation to reality. The government may think they have a plan and an idea of how things will start to turn but from what I have seen they have no understanding at present.
My understanding of the situation is that it is currently driven by the fact that the NHS is now unable to cope but it will take another four or five days for that to become so apparent that complete lockdown in London will be inevitable. Maybe medical staff will walk out (mostly on an individual basis I suspect) when they see one or two more news items on their colleagues in Italy.
If things are locked down the current peak will start to go down in about ten days I think. By that time a bit more sense may prevail and it may go on going down. As to what happens next I have no idea but if the government relaxes things again too soon we will be back to where we are now pretty sharpish - within a month at most.
I am pretty sure that fairly soon what happens in the UK will just be dictated by the experience in Italy and also France, Spain and Germany. It should have done a month ago. So Whitty and Vallance will become irrelevances.
I guess one problem with the modelling in the UK is the fact that there is no testing of people in the community who have symptoms and no testing of their contacts (regardless of whether they have symptoms) so you don't have the data to populate a model. You probably only have outcomes i.e. people who are hospitalised but the number of people hospitalised doesn't really tell you how the rate of transmission is increasing.