foxp3 is relevant for MS could other fox genes be relevant for me/cfs I never see this mentioned and think it might be worth a look https://multiplesclerosisnewstoday....sponses-in-multiple-sclerosis-other-diseases/ interesting as well https://multiplesclerosisnewstoday....rogressive-multiple-sclerosis-in-early-study/ A tricyclic antidepressant especially used in ocd Interesting bit on YouTube about history of FOXP3 and Manhattan project
Was the foxp3 (scurfy mouse) mutation discovered around the Manhattan project really just coincidence or was it an effect of radiation Foxc1 seems to have a dose effect with over and under expression,over expression association with breast cancer and leukaemia,not sure what under expression leads to. Many shades of foxc1 expression
FOXC1 target genes https://academic.oup.com/hmg/article/17/4/490/2355979 They use mifepristone to Stimulate FOXC1 in the paper,I find it interesting that this was trialed as a treatment in GWS,I presume it would stimulate FOXC1 FOX01a effect on FOXP3 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034255/
Is there a chance FOXC1 could be a candidate gene for ME as it effects about 600 other genes and is linked to breast cancer and leukaemia Autism is strongly linked as well EBV reduces FOXO1 expression It also brings together many different angles Figure 2. https://academic.oup.com/hmg/article/17/4/490/2355979/
