Hybrid immunity

Mij

Mij

Senior Member (Voting Rights)
"What happens when previously infected individuals are vaccinated? The observations in several studies, including those by Stamatatos et al. and Reynolds et al., are that an impressive synergy occurs—a “hybrid vigor immunity” resulting from a combination of natural immunity and vaccine-generated immunity. When natural immunity to SARS-CoV-2 is combined with vaccine-generated immunity, a larger-than-expected immune response arises".

https://science.sciencemag.org/content/372/6549/1392
 
When I booked my second vaccine appointment, I was offered either a second dose of the Pfizer vaccine, or a dose of the other one (starts with an 'M'), which is supposed to be just as effective. I did ponder whether ME might cause problems with a different vaccine or with a second dose of the same one. I doubt that there's anyone in the world who can answer that question, so I went for option two, since it's more available. Even if I do get a severe reaction, I won't know whether the other option would have been better.
 
I wasn't able to read the document properly, but there seems to be no reference to auto-immunity or adverse effects. Does anyone know if there are? (I searched the page.)

I want to know if there are adverse effects in auto-immune people, as many of us are. (I'm fairly sure that I have had the virus too.)
 
Creekside said:
When I booked my second vaccine appointment, I was offered either a second dose of the Pfizer vaccine, or a dose of the other one (starts with an 'M'), which is supposed to be just as effective. I did ponder whether ME might cause problems with a different vaccine or with a second dose of the same one. I doubt that there's anyone in the world who can answer that question, so I went for option two, since it's more available. Even if I do get a severe reaction, I won't know whether the other option would have been better.
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Was it Moderna?
 
Now Published:

Tolerance of Covid-19 vaccination in pts with SLE(Lupus) in the international VACOLUP study:

In conclusion, the VACOLUP study suggests that COVID-19 vaccination appears well tolerated in patients with SLE, with only a minimal risk of flare, if any, including after the mRNA vaccines. Willingness to get vaccinated against COVID-19 in patients with autoimmune diseases is limited by the fear of side-effects and the paucity of available data.
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Therefore, disseminating these reassuring data might prove crucial to increasing vaccine coverage in patients with SLE.
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https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(21)00221-6/fulltext
 
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