Immune cells play a bigger role in high blood pressure than previously thought, opening doors for new treatments

Sly Saint · Jul 2, 2024 at 11:01 AM

Hypertension is one of the most prevalent non-transmittable diseases in the world, with 29% of the world's population expected to suffer from the condition by 2025. Despite substantial advances in anti-hypertensive interventions, a majority of patients continue to suffer from the condition's comorbidities, suggesting that traditional interventions fail to target the root cause of hypertension.

In a recent review published in the journal Nature Reviews Nephrology, researchers collate and discuss a growing body of literature investigating the role of immune cells in hypertension's pathogenesis and progression. They highlight that hypertension arises from chronic, dysregulated inflammation caused by various immune cells, both adaptive and innate. Encouragingly, this review suggests that immune responses, and by extension hypertension, may be amenable to future therapeutic interventions. However, caution must be exercised while identifying key antigens and immune regulatory nodes to prevent compromising patients' natural immune defenses.
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Immune cells play a bigger role in high blood pressure than previously thought, opening doors for new treatments (msn.com)

MeSci · Jul 2, 2024 at 2:42 PM

I haven't had time to read the article yet, but just thought I'd post what I have posted elsewhere - that my hypertension, and my polyuria, have both gone, after suffering for many years and taking drugs for them. I wonder whether they were due to dental problems. I talk about it here:

https://www.s4me.info/threads/diarrhoea-caused-by-too-much-desmopressin.36981/#post-521077

(Unfortunately I have diarrhoea again...)

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Immune cells play a bigger role in high blood pressure than previously thought, opening doors for new treatments

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Immune cells play a bigger role in high blood pressure than previously thought, opening doors for new treatments

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