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Mechanistic Insights into the Pathophysiology of CFS/ME: Examining Nrf2 Antioxidant Gene Expression & its Role in Combating Oxidative Stress, ongoing

Discussion in 'ME/CFS research' started by Andy, Mar 23, 2019.

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  1. Andy

    Andy Committee Member

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    Struggling at the moment to find more details about this, if/when I do I'll edit them in here.

    From https://cureme.lshtm.ac.uk/researchers/our-collaborative-researchers/
    https://twitter.com/user/status/1109401905095049217


    ETA: Added detail from the CureME collaborators page.
     
    Last edited: Mar 23, 2019
    Andy, Mar 23, 2019
    #1
    Snowdrop, Peter Trewhitt, Ron and 8 others like this.
  2. Amw66

    Amw66 Senior Member (Voting Rights)

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    Dundee was where muscle research for children with "CFS" was done . Tymes promoted it, think it was funded by ME Research or Invest .

    Dundee has done a bit of oaedupaedi research in conjunction with TT.
    http://www.meresearch.org.uk/our-research/completed-studies/impact-in-childhood/

    Perhaps moving into adults?

    Eta link. Will try and find muscle study
     
    Amw66, Mar 23, 2019
    #2
    Peter Trewhitt, shak8, Ron and 2 others like this.
  3. Andy

    Andy Committee Member

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    This is their previous work on the same subject.
    http://www.meresearch.org.uk/our-research/ongoing-studies/combat-oxidative-stress/
     
    Andy, Mar 23, 2019
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    Peter Trewhitt, shak8, Ron and 5 others like this.
  4. mariovitali

    mariovitali Senior Member (Voting Rights)

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    It sounds like very interesting work.
     
    mariovitali, Mar 23, 2019
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    Ron likes this.
  5. lansbergen

    lansbergen Senior Member (Voting Rights)

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    Their main finding, however, has been that people with ME/CFS have high levels of reactive oxygen molecules, which can harm blood vessels and muscles.

    I am pretty sure in my case they are skyhigh during flares.
     
    lansbergen, Mar 23, 2019
    #5
    Peter Trewhitt, Ron, Amw66 and 1 other person like this.

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