Neuroscience News: Is a Stress Shot on the Horizon?

Andy

Retired committee member
Based on mice research but at least sounds interesting.
Summary: An immunization for stress created from beneficial bacteria could be on the horizon. The vaccine is said to have long lasting anti-inflammatory effects, making people more resilient to the psychological and physical effects of stress.

Source: University of Colorado at Boulder.

Immunization with beneficial bacteria can have long-lasting anti-inflammatory effects on the brain, making it more resilient to the physical and behavioral effects of stress, according to new research by University of Colorado Boulder scientists.

The findings, if replicated in clinical trials could ultimately lead to new probiotic-based immunizations to protect against posttraumatic stress disorder (PTSD) and anxiety or new treatments for depression, the authors say.

“We found that in rodents this particular bacterium, Mycobacterium vaccae, actually shifts the environment in the brain toward an anti-inflammatory state,” said lead author Matthew Frank, a senior research associate in the Department of Psychology and Neuroscience. “If you could do that in people, it could have broad implications for a number of neuroinflammatory diseases.”
https://neurosciencenews.com/stress-vaccine-9279/
 
After exposure to a stressor, the immunized animals also showed lower levels of a stress-induced protein, or alarmin, called HMGB1, believed to play a role in sensitizing the brain to inflammation, and higher expression of CD200R1, a receptor key for keeping glial cells (the brain’s immune cells) in an anti-inflammatory state.

My bold. Very interesting indeed.
 
way to simplistic biochemistry that has taken millions of years to develop can not be simplified to this extent by wishful thinking . stress is a natural part of living who knows how many serious complications will arise from tinkering with one or two different pathways. we need a far more complete understanding of human biology on the macro scale than is presently available .
 
way to simplistic biochemistry that has taken millions of years to develop can not be simplified to this extent by wishful thinking . stress is a natural part of living who knows how many serious complications will arise from tinkering with one or two different pathways. we need a far more complete understanding of human biology on the macro scale than is presently available .
This is the risk, instead of understanding emotions and learning what they are trying to tell us we want to become a society of fast food and buried wisdom. Feel depressed, why doesn't matter, take a pill, feel stressed, instead of fixing the cause you can wash it away instead.
Easy answers are the only answers you need...
 
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