New-onset chronic musculoskeletal pain following COVID-19 infection fulfil the Fibromyalgia clinical syndrome criteria, 2024, Omar Khoja et al

Mij

Senior Member (Voting Rights)
Abstract
Background: New-onset chronic musculoskeletal (MSK) pain (> 3 months duration) is one of the commonest persistent symptoms of Post-COVID syndrome (PCS). There is emerging evidence that the chronic MSK pain and associated symptoms in PCS have similarities to Fibromyalgia Syndrome (FMS).

This study aimed to characterize PCS related new-onset chronic MSK pain and its overlap with Fibromyalgia Syndrome (FMS).

Methods: Patients with new-onset chronic MSK pain following COVID-19 infection were enrolled and the nature of pain and associated symptoms captured using the C19-YRS (Yorkshire Rehabilitation Scale). FMS assessment was conducted as part of standard clinical examination using the American College of Rheumatology (ACR) 2010 criteria. Diagnosis of FMS was made when they meet the standard criteria of (1) Widespread Pain Index (WPI) ≥ 7 and Symptoms Severity (SS) score ≥ 5, or WPI is 3-6 and SS score ≥ 9, (2) symptoms have been present at a similar level for at least 3 months, and (3) the patient does not have a disorder that would otherwise explain the symptoms.

Results: Eighteen patients, twelve of whom were female, with an average age of 49.6 (SD 11.8) years and a Body Mass Index of 31.7 (SD 8.6) were enrolled. The average duration of symptoms from COVID-19 infection to assessment was 27.9 (SD 6.97) months. The new-onset chronic pain was widespread, primarily manifesting as muscle pain. Thirteen (72.2%) patients met the diagnostic criteria for FMS, with an average WPI score of 8.8 and an average SS score of 8.2, indicating a high level of pain and significant adverse impact on their quality of life.

Conclusion: The study found that 72.2% of the patients with new-onset chronic MSK pain following COVID-19 infection met the criteria for FMS. These findings support the hypothesis that FMS may develop as a long-term sequela of a viral infection, underscoring the need for further research into post-viral long-term conditions.

LINK
 
Senior author is Manoj Sivan. He's recently been the senior author on a number of papers of interest to us. His background is in rehabilitation medicine:

Manoj graduated in Medicine (MBBS) in 1999. After junior medical and surgical training in Cardiff, Reading, Oxford, Leicester and Cambridge, he took up UK's first academic registrar training post in Rehabilitation Medicine (NIHR Academic Clinical Fellow) in Leeds in 2007. He completed his MD (Research) in rehabilitation robotic technology, and the work was awarded two prestigious prizes in 2014 (European Academy of Rehabilitation Medicine (EARM) and Philip Nichols). He then worked as a consultant at Salford Royal Hospital from 2012 to 2017. From 2017-2024, he worked as Associate Clinical Professor at the University of Leeds & NHS consultant at Leeds Hospitals and an honorary Senior Lecturer at the University of Manchester. He was promoted to Clinical Professor at the University of Leeds & NHS consultant at Leeds Hospitals in 2024.
He was appointed President of the British Society of Physical and Rehabilitation Medicine BSPRM (https://www.bsprm.org.uk/) in Nov 2022.

He is the Editor-in-Chief of the SAGE journal Advances in Rehabilitation Science and Practice (https://journals.sagepub.com/home/rpo) and the Oxford Handbook for Rehabilitation Medicine (https://academic.oup.com/book/29871)

He has served as an advisor for the World Health Organisation (WHO) Europe – Disability and Rehabilitation during the pandemic.

Research interests: Rehabilitation technology; Pain Medicine; Autonomic Medicine; Musculoskeletal and Sport and Exercise Medicine; Neurological Rehabilitation; Diagnostic and Interventional Ultrasound; Measurement of Health Outcomes

He's recently got funding for a project on
Evaluation of outcomes from NHS England Long COVID services using ELAROS digital PROM data
 
Back
Top Bottom