https://link.springer.com/chapter/10.1007/978-3-030-57231-0_32 PET/SPECT/MRI/fMRI Studies in the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Yasuyoshi Watanabe Chapter First Online: 15 December 2020 547 Accesses 3 Citations Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a serious, debilitating disorder with a wide spectrum of symptoms, including fatigue, pain, depression and neurocognitive deterioration. Over 17 million people around the world have ME/CFS, predominantly women with peak onset at 30–50 years. Given the wide spectrum of symptoms and unclear etiology, specific biomarkers for diagnosis and stratification of ME/CFS are lacking. Here the results from PET/SPECT/MRI/fMRI studies are reviewed to understand the pathophysiology and to develop therapies of this severe syndrome. Keywords Myalgic encephalomyelytis/chronic fatigue syndrome Brain morphometry Connectivity Regional cerebral blood flow Glucose utilization rate Serotonergic deterioration Neuroinflammation Repair energy loss --- I've heard it's available here: https://sci-hub.se/