Trial Report Plasma cell targeting with the anti-CD38 antibody daratumumab in ME/CFS -a clinical pilot study, 2025, Fluge et al

[V.R.T.]

Have you checked the protocol document? They update this periodically.

No I haven't- I don't have the capacity to find the link right now though. Do you have it to hand?

 

[fst]

No I haven't- I don't have the capacity to find the link right now though. Do you have it to hand?

Search for clinical trials - EMA

No new update. But I don't think that means anything at this moment. Don't think they'd put the results in there before submitting the paper.

 

[SugarSquared]

Yeah, at this point, I expect to hear nothing until the phase II trial is done. They might be worried about introducing bias by sharing results, even if it’s from another study (if I understand you right).

 

[V.R.T.]

Yeah, at this point, I expect to hear nothing until the phase II trial is done. They might be worried about introducing bias by sharing results, even if it’s from another study (if I understand you right).

I dont think that they are worried about that - they released the results of the long COVID patients they gave less doses to last winter.

I always understood the plan was to release the results of this pilot expansion as and when it was done otherwise, why not make it part of the phase two?

The strong implication was that they would be releasing these results from the smaller groups as and when they were ready.

 

[Utsikt]

My reading of the updates they have provided on ResetME is that the recruitment process has required a lot of resources. I would not be surprised if there are delays to processing and disseminating the severe data because they’ve prioritised the bottlenecks for ResetME.