They believe something may be wrong with a central control system in the body. If this can be corrected, there may be no need for a new drug.
He has only done the nanoneedle test on 10 patients (?) I wonder if he might consider trying it out on a couple of Nancy Klimas GWI patients. If it proved negative then that would go towards showing it is a good test for ME, and if positive then maybe some of the GWI funding might help to develop it further.
but I don't think that is what the nanoneedle test is testing (as far as I remember even Prof Davis doesn't know why the test works; something to do with impedance).There's a thread somewhere that discusses the deformability of red blood cells and GWI.(posted below)
If I have this right, Ron Davis' (with San Jose Univ) research shows the red blood cells do not deform as necessary to fit along narrow capillaries so that full oxygen is not being picked up. Blood is purplish and viscous.
The research on GW patients shows the opposite.
https://www.s4me.info/threads/abnor...s-a-preliminary-study-2018-condon-et-al.3707/
https://www.omf.ngo/2018/03/21/omf-funded-research-red-blood-cell-deformability-in-me-cfs/
but I don't think that is what the nanoneedle test is testing (as far as I remember even Prof Davis doesn't know why the test works; something to do with impedence).
eta: this is the test he does by stressing the cells out with salt(?)
http://www.meaction.net/wp-content/uploads/2015/05/Ron-Davis-Transcript.pdfDr. Ron Davis said:So, if we put healthy cells and their serum into the device, it is pretty stable and does not change. If we put in ME/CFS cells and their serum, it doesn’t change. However, if we put a demand on the cells, we require them to consume energy, and that demand is seen in this graph where there is a slight dip in the healthy controls – but they handle that demand quite well and don’t change after that – however the cells from the ME/CFS patient, show a rapid increase in impedance. And that has been shown for every patient we have looked at, and also every healthy control is the same.
The URL suggests that talk is from 2015, but I thought it was more recent than that.That's all very exciting. I don't want to get my hopes up, but I really hope he can share more info soon. We need a little bit of sunshine.