Symptoms of Covid-19

Mild initial symptoms of loss of taste & diarrhoea then rapid deterioration...
https://www.google.com.au/amp/s/amp...d-words-brought-him-back-20200508-p54ran.html

 

Interesting informal analysis from a community survey: https://docs.google.com/document/d/1KmLkOArlJem-PArnBMbSp-S_E3OozD47UzvRG4qM5Yk/edit#.

An Analysis of the Prolonged COVID-19 Symptoms Survey by Patient-Led Research Team

It's very ad hoc but still an impressive effort. Formal studies of this will be very slow as this is low on everyone's radar. Good idea to put it out there quickly.

Highlights:

As is predictable, the confusion and uncertainty mixed with disbelief are causing quite a lot of distress. So much for the belief that diagnosing this is what causes the unhelpful beliefs...

The survey is obviously biased in favor of those who did not recover, so this is only representative of that subset of unfortunates.

The report evaluated 62 symptoms and still got written answers:

(Ramsay's research flashing in the background)

 

U.K. will now be using loss of smell or taste as a symptom of COVID-19. (See NHS announcements).

so that means you need to have one of the following:
-fever
-continuous cough
- loss of smell or taste

to have suspected coronavirus (and presumably, to get a test).

However we know from other countries & from the symptom tracker app that many DON’T have these symptoms And still have coronavirus. So although they’ve recognised loss of smell and taste (only a few months too late...), It’s still not enough.

 

Hallelujah. How many weeks ago was it that I read about the anecdotal evidence about anosmia in, I think, the Washington Post? Feels like a couple of months. Just think of all the people who have become unnecessarily infected in the interim Better late than never.

 

Merged thread

Coronavirus: 'Baffling' observations from the front line - article from BBC News 23/05/20

When you talk to intensive care doctors across the UK, exhausted after weeks of dealing with the ravages of Covid-19, the phrase that emerges time after time is, "We've never seen anything like this before."

They knew a new disease was coming, and they were expecting resources to be stretched by an unknown respiratory infection which had first appeared in China at the end of last year.

And as the number of cases increased, doctors up and down the UK were reading first-hand accounts from colleagues in China, and then in Italy - in scientific journals and on social media - about the intensity of infection.

"It felt in some ways like we were trying to prepare for the D-Day landings," says Barbara Miles, clinical director of intensive care at Glasgow Royal Infirmary, "with three weeks to get ready and not a great deal of knowledge about what we would be facing".

But what arrived in the UK as winter turned into spring took even the most experienced ICU specialists by surprise.

https://www.bbc.co.uk/news/52760992

 

It may not be relevant to this thread, or even correct, but I know I've seen ME sometimes mentioned in conjunction with "diffuse encephalitis" or a "diffuse inflammation of the brain," such as here in a 2007 article written by Malcolm Hooper.

I've also seen this idea dismissed on the basis that encephalitis is too deadly to be associated with ME, though there are mild forms of viral encephalitis that only cause flu-like symptoms. Perhaps the objection is to the notion of a chronic encephalitis.

 

I've long been suggesting that ACE2 dysregulation is the key problem, but I doubt very much that it is genetics that will explain the variance.

 

I've been pretty confused about the effect, one way or the other, of taking ACE (Angiotensin-converting enzyme) inhibitors or ARB's (Angiotensin II Receptor Blockers) vis-a-vis COVID-19.

This pre-print paper out of Yale University has not been peer-reviewed yet, but in a study of about 10,000 patient records it found that -

[my bold]

So, the only effect seems to be that ACE inhibitors reduce hospitalizations by almost 40%, if you're over 65 (which would be good news, if confirmed).

The paper: https://www.medrxiv.org/content/10.1101/2020.05.17.20104943v1

Article about the paper: https://news.yale.edu/2020/05/27/se...ce-inhibitors-have-lower-hospitalization-risk


Of course, the views on this could all change by tomorrow...

 

well, they're tracking an association, so we don't know that it's a causal relationship. Very likely those of Medicare age who took them were different than those who didn't take them in multiple ways.

 

True. If nothing else, taking an ACE inhibitor implies you have an ongoing relationship with a doctor - although that would also be true for ARB's, which showed no effect.

 

I doubt the wisdom of taking ACE inhibitors without checking one's blood sodium levels, as they tend to reduce them, in my own case very significantly - I ended up with severe hyponatraemia. Just saying for anyone who doesn't know.

 

It goes without saying that no one should even consider starting or stopping a medication based on a single study that has not even gone through peer review yet.

I just thought the paper represented an interesting contradiction to earlier speculation I'd seen suggesting that ACE inhibitors might somehow make COVID-19 worse. That's what I meant when I said that the views on this could all change again tomorrow.

 

Another summary of long-term symptoms. (Warning: they are indeed "scary")

http://www.msn.com/en-gb/health/min...ow/ss-BB14IzPd?li=AAnZ9Ug&ocid=ASUDHP#image=2

 

Petition: Revise COVID-19 Guidelines to Accurately Reflect Recovery Periods
https://www.change.org/p/world-heal...elines-to-accurately-reflect-recovery-periods

 

Finally managed to track down this rather natty summing-up of symptoms which appeared in my local newspaper:

https://images.app.goo.gl/8jeDL9NL1EnZNGBaA

NB: "My" version also has at bottom left:

"Do not leave home if you or someone you live with has any of the following:
- A high temperature
- A new, continuous cough
- A loss of, or change to, your sense of smell or taste.

 

Apparently another 3 symptoms have officially been added to the list:

http://www.msn.com/en-gb/health/med...-had-virus/ar-BB163xPT?li=AAnZ9Ug&ocid=ASUDHP

 

thats interesting, because before I had seen that it was determined “rare” to have a runny nose and congestion. (This is in the USA, I wonder if U.K. will update)?

 

Finally GI symptoms. Took them long enough. At this pace they'll have them all sometime by 2025. You know, with genuine patient-led medicine, this would go much faster. It's tedious having to wait for people to catch up to things that have been obvious for months.

It's interesting to see runny nose because initially there was a belief that it was not part of it, as in almost an exclusionary factor likely hinting at another respiratory infection.