Abstract Many studies of patients with long-standing chronic fatigue syndrome (CFS) have found alterations to the hypothalamo-pituitary-adrenal (HPA) axis, including mild hypocortisolism, heightened negative feedback and blunted responses to challenge. However, recent prospective studies of high-risk cohorts suggest that there are no HPA axis changes present during the early stages of the genesis of fatiguing illnesses. Moreover, HPA axis changes can be reversed by modifying behavioural features of the illness, such as inactivity, deconditioning and sleep disturbance. Nevertheless, raising levels of cortisol pharmacologically can temporarily alleviate symptoms of fatigue. This article presents the case that there is no specific change to the HPA axis in CFS and that the observed changes are of multifactorial aetiology, with some factors occurring as a consequence of the illness. Nevertheless, the HPA axis might play a role in exacerbating or perpetuating symptoms late on in the course of the illness. Link paywall
Yeah - where is his proof that he reversed illness by enforcing behaviours. Who is betting drop outs were very high and miraculously the group who got thru the krypton factor were fitter than the full group before the illest were jettisoned? or that it’s just been asserted with no actual test of that statement itself at all but ‘those who could change it were weller’ just like cancer patients who were able to continue to do their running training to the end of their treatment were those whose treatment worked for their cancer is different to suggesting running was part of the cure for all
Yes, it it can for some people, temporarily. So can many other things that aren't corticosteroids. Whacking a malfunctioning piece of electrical equipment can sometimes temporarily get it working again, but that doesn't mean that the equipment was suffering from whack deficiency.
You will never be taken seriously by the pros with that kind of amateur ignorance. The correct technical term is 'percussive maintenance'.
