cortisol

Stress-induced changes in LPS-induced pro-inflammatory cytokine production in chronic fatigue syndrome Gaab, Jens; Rohleder, Nicolas; Heitz, Vera; Engert, Veronika; Schad, Tanja; Schürmeyer, Thomas H.; Ehlert, Ulrike OBJECTIVE It has been suggested that a hypofunctional...

Associations between neuroendocrine responses to the Insulin Tolerance Test and patient characteristics in chronic fatigue syndrome Gaab, Jens; Engert, Veronika; Heitz, Vera; Schad, Tanja; Schürmeyer, Thomas H; Ehlert, Ulrike Objective Subtle dysregulations of the...

Hypothalamo-Pituitary-Adrenal Axis Dysfunction in Chronic Fatigue Syndrome, and the Effects of Low-Dose Hydrocortisone Therapy Cleare, A. J.; Miell, J.; Heap, E.; Sookdeo, S.; Young, L.; Malhi, G. S.; O’Keane, V. Abstract These neuroendocrine studies were part of a series of studies testing...

Naloxone-mediated activation of the hypothalamic–pituitary–adrenal axis in chronic fatigue syndrome L.V. Scott, F. Burnett, S. Medbak, T.G. Dinan Background Opioidergic pathways have an inhibitory regulatory influence on the hypothalamic–pituitary–adrenal axis (HPA) in man. Previous studies...

Blunted adrenocorticotropin and Cortisol responses to corticotropin‐releasing hormone stimulation in chronic fatigue syndrome Scott, L. V.; Medbak, S.; Dinan, T. G. Abstract Hyperfunctioning of the pituitary‐adrenal axis has been suggested as the pathophysiological basis for chronic fatigue...

Hair cortisol concentration and basal heart rate variability differentiate long COVID from depressive disorders in youth Oehlke, S.-M.; Lozar, A.; Goreis, A.; Klinger, D.; Nater, U.M.; Skoluda, N.; Binder, H.; Plener, P.L.; Kothgassner, O.D. Highlights • Despite clinical overlap, long...

Serum Proteomic Profiling Reveals Renin-Associated Immune and Cytoskeletal Dysregulation in Post-COVID-19 Condition Patients with Secondary Adrenal Insufficiency Abstract Post-COVID-19 condition (PCC) with secondary adrenal insufficiency (SAI) involves multiorgan dysfunction, potentially...

The increase of alpha-melanocyte-stimulating hormone in the plasma of chronic fatigue syndrome patients Background Despite extensive research, no reliable biological marker for chronic fatigue syndrome (CFS) has yet been identified. However, hyperactivation of melanotrophs in the pituitary...

Contrasting neuroendocrine responses in depression and chronic fatigue syndrome Abstract Hypothalamic-pituitary-adrenal (HPA) axis and central 5-HT function were compared in chronic fatigue syndrome (CFS), depression and healthy states. 10 patients with CFS and 15 patients with major...

The Use of a Handheld Non-Invasive Vagal Nerve Stimulation nVNS Device for the Treatment of Long COVID: A Pilot Randomized Controlled Trial OBJECTIVES Long-term symptoms following infection with acute respiratory syndrome coronavirus-2 (SARS-CoV-2), termed post-acute sequelae of SARS-CoV-2...

Diurnal Variation of Adrenocortical Activity in Chronic Fatigue Syndrome (Note: old paper) Abstract Baseline morning and evening serum cortisol and ACTH concentrations, and diurnal changes in hormone levels, were measured in 30 patients with chronic fatigue syndrome (CFS) but without...

Core body temperature is normal in chronic fatigue syndrome (note: old paper) Abstract Background: Subjects with chronic fatigue syndrome (CFS) frequently report symptoms of subnormal body temperature and low-grade fever. We conducted a study to determine whether CFS subjects manifest any...

Systems neuroendocrinology in ME/CFS and long COVID: a chronobiological framework for hormone-based research Hormonal dysregulation is increasingly reported in ME/CFS and Long COVID, yet the broader role of neuroendocrine disruption in these conditions remains underexplored. While changes in...

Characterization of pituitary function with emphasis on [Growth Hormone] secretion in the chronic fatigue syndrome Abstract OBJECTIVE Previous studies have revealed that hormonal disturbances may accompany the chronic fatigue syndrome (CFS). Changes in the secretion of the pituitary–adrenal...

Link to post with final paper abstract - post #13 Preprint Analysis Of Salivary Herpesviruses Reveals Associations Between HHV-6 And Long COVID Severity BACKGROUND Reactivation of human herpesviruses (HHVs), particularly EBV, is associated with more severe acute SARS-CoV-2 infections and the...

Reproducibility of the circadian rhythms of serum cortisol and melatonin in healthy subjects: a study of three different 24-h cycles over six weeks Selmaoui, Brahim; Touitou, Yvan Abstract Plasma melatonin and cortisol are characterized by a marked circadian rhythm, but little information is...

Evidence for Impaired Activation of the Hypothalamic-Pituitary-Adrenal Axis in Patients with Chronic Fatigue Syndrome Abstract Chronic fatigue syndrome is characterized by persistent or relapsing debilitating fatigue for at least 6 months in the absence of a medical diagnosis that would...

Making a thread to start collecting some of the CRH ideas floating around. Everyone free to add anything that seems relevant. Note there is also jnmaciuch's Peripheral neurons, CRH, and sickness behavior thread, which is a bit more focused. I'll probably come back and clean up this first post...

This table is based off the Cortisol levels in ME/CFS thread. This is a rough draft. Feedback welcome, the only caveat being I probably don't want to add too much info to each line. Will add a blurb with some version of this caveat: Daily studies of cortisol in ME/CFS patients need to be...

Neuroendocrine signature of ME/CFS: Meta-analytic evidence for bioactive cortisol deficit and exaggerated feedback sensitivity Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a major clinical challenge as a complex multisystemic disorder with no well-established...