https://www.neurologyadvisor.com/to...nfusion-for-patients-with-ms-related-fatigue/ Primary outcome of the study was negative. Reference Fitzgerald KC, Morris B, Soroosh A, et al. Pilot randomized active-placebo-controlled trial of low-dose ketamine for the treatment of multiple sclerosis–related fatigue. Mult Scler. Published online July 7, 2020. doi:10.1177/1352458520936226