treatment

  1. Nightsong

    Efficacy and safety of rivaroxaban, colchicine, and famotidine–loratadine with specialist supportive clinical care for fatigue..., 2026, STIMULATE-ICP

    Efficacy and safety of rivaroxaban, colchicine, and famotidine–loratadine with specialist supportive clinical care for fatigue in patients with post-COVID-19 condition in the UK: a multisite, open-label, randomised controlled trial (STIMULATE-ICP consortium) Abstract: Background Post-acute...
  2. Dolphin

    Trial Report Effect of L-citrulline supplementation on endothelial function and body composition in post-COVID-19 syndrome: a RCT, 2026, Salgado-Fernández

    Free fulltext: https://www.mdpi.com/2072-6643/18/11/1706 CABI Databases Abstract record 21 June 2026 Effect of L-citrulline supplementation on endothelial function and body composition in post-COVID-19 syndrome: a randomized clinical trial. Journal article: Nutrients, 27 May 2026, Vol. 18...
  3. J

    GLP-1s for Long COVID and ME—survey results

    https://lcmedata.org/treatments/glp1s Polarizing results: 53% improved, 20% no change, 28% worsened Brain fog (44%), fatigue (37%), exercise tolerance (27%) most commonly improved symptoms Top side effects: nausea (30%), constipation (20%), post-dose fatigue (19%) POTS subtypes fared worst...
  4. Hutan

    Trial Report The Effect of Fluvoxamine and Metformin for Fatigue in Patients With Long COVID, 2026, Reis et al

    The Effect of Fluvoxamine and Metformin for Fatigue in Patients With Long COVID Abstract Abstract Background and Objective: Postacute sequelae of SARS-CoV-2, or long COVID, presents a major therapeutic challenge, with fatigue being a prevalent and debilitating symptom. Objective: To assess...
  5. T

    News from Canada

    This thread is for news about ME/CFS and related topics from Canada Post copied from this thread: ME/CFS: Organic Disease or Psychosomatic Illness? A Re-Examination of the Royal Free Epidemic of 1955, Underhill & Baillod, 2020 which discusses the study noted below...
  6. Andy

    Trial Report Transcutaneous electrical nerve stimulation and pain with movement in people with fibromyalgia: a cluster randomized clinical trial 2026 Dailey et al

    Key Points Question Is transcutaneous electrical nerve stimulation (TENS) effective for treating pain when combined with physical therapy (PT) in individuals with fibromyalgia? Findings This cluster randomized clinical trial of 459 participants with fibromyalgia from 28 PT clinics from 6...
  7. J

    Preprint Microtesla Magnetic Therapy for cognitive impairment in post-acute sequelae of SARS CoV-2: A randomized controlled feasibility study Canori Putrino

    Abstract Background: Cognitive impairment has significant implications for function and quality of life and is common in individuals with post-acute sequelae of SARS CoV-2, also known as long COVID (LC). Emerging evidence suggests that sustained neuroinflammation, cerebrovascular dysfunction...
  8. Mij

    Taurine [...] as a therapeutic strategy for cellular senescence and chronic inflammation in LC: a systematic review and meta-analysis, 2026 Wang et al

    Abstract Background SARS-CoV-2 infection can induce cellular senescence, resulting in chronic inflammation and senescence-associated secretory phenotype observed in post-acute sequalae of COVID-19 (PASC). Taurine, a conditionally essential amino acid with potent anti-inflammatory and...
  9. SNT Gatchaman

    Trial Report Neither Metformin nor Ursodeoxycholic Acid Effectively Treats Postacute Sequelae of COVID-19, 2026, Lim et al.

    Neither Metformin nor Ursodeoxycholic Acid Effectively Treats Postacute Sequelae of COVID-19 BACKGROUND There is no proven treatment to alleviate symptoms of postacute sequelae of SARS-CoV-2 infection (PASC), despite its substantial public health burden. OBJECTIVE To evaluate the efficacy of...
  10. Dolphin

    Review Systematic literature review: treatment of postural orthostatic tachycardia syndrome (POTS) [with a special focus on POTS in ME/CFS], 2025, Schiweck

    https://link.springer.com/article/10.1007/s10286-025-01172-2 Systematic literature review: treatment of postural orthostatic tachycardia syndrome (POTS) Review Article Open access Published: 12 November 2025 (2025) Nicole Schiweck, Katharina Langer, Andrea Maier, Daniel Vilser & Juliane...
  11. Sly Saint

    Article: Nasal spray developed to treat life-threatening allergic reactions is now available in UK

    https://www.dailymail.co.uk/health/article-15250035/Nasal-spray-life-threatening-allergic-reactions-UK.html
  12. S

    Water drinking as a treatment for orthostatic syndromes, 2002, John R Shannon et al

    Water drinking as a treatment for orthostatic syndromes John R Shannon, Andre Diedrich, Italo Biaggioni, Jens Tank, Rose Marie Robertson, David Robertson, Jens Jordan Abstract Purpose: Water drinking increases blood pressure in a substantial proportion of patients who have severe...
  13. Sly Saint

    Article: Biology teacher becomes first UK patient to receive ‘gamechanger’ therapy for MS

    https://www.msn.com/en-gb/health/medical/biology-teacher-becomes-first-uk-patient-to-receive-gamechanger-therapy-for-ms/ar-AA1P4nc7?ocid=msedgntp&pc=U531&cvid=68fb7249618f479794914ca2e693c6df&ei=10 https://www.independent.co.uk/news/health/multiple-sclerosis-gamechanger-therapy-nhs-b2850928.html
  14. M

    The scientific basis for fatigue, 2025, Martin et al.

    Book: The scientific basis of fatigue, 2025, Martin et al. [Need to edit cause need to figure out how to add tags] About the book Key Features Reviews molecular and cellular aspects of chronic fatigue syndrome Outlines fatigue in relation to various conditions including diabetes, Parkinson’s...
  15. forestglip

    Trial Report Feasibility and tolerability of dual-target [rTMS] for treatment of [ME/CFS]: An open label pilot study, 2025, Corlier et al

    Feasibility and tolerability of dual-target repetitive transcranial magnetic stimulation (rTMS) for treatment of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): An open label pilot study Juliana Corlier, Hrag Peltekian, Thomas E. Valles, Cole D. Matthews, Doan Ngo, Reza...
  16. S

    Treatment - morphine for severe pain

    Can I ask if anyone has been given morphine to help with their dire pain and malaise. I’m taking codeine and pregablin plus duloxetine and nortriptyline. But I’m in dire agony now nearly all of the time. I’ve had a small bit of a friends morphine which helped me immensely but as yet cannot get...
  17. Ravn

    Review A Perspective on the Role of Metformin in Treating [...] (ME/CFS) and Long COVID (2025) Fineberg et al

    Authors: David Fineberg, Alain Moreau, Elena K Schneider-Futschik, Christopher W. Armstrong Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Long COVID (LC) are increasingly recognized as debilitating postinfectious conditions that impact both individuals and society...
  18. Dolphin

    Trial Report Pacing, conventional physical activity and active video gaming to increase physical activity levels for ME/CFS: pilot feasibility study, 2025, Tarca +

    https://www.degruyterbrill.com/document/doi/10.1515/teb-2025-0017/html Pacing, conventional physical activity and active video gaming to increase physical activity levels for adults with myalgic encephalomyelitis/chronic fatigue syndrome: a pilot feasibility study Brett Tarca , Kade Davison ...
  19. Dolphin

    Tonix Pharmaceuticals Announces FDA Approval of Tonmya™ (cyclobenzaprine HCl sublingual tablets) for the Treatment of Fibromyalgia

    Tonmya is the first FDA-approved therapy for the treatment of fibromyalgia in over 15 years https://www.globenewswire.com/news-release/2025/08/15/3134450/28908/en/Tonix-Pharmaceuticals-Announces-FDA-Approval-of-Tonmya-cyclobenzaprine-HCl-sublingual-tablets-for-the-Treatment-of-Fibromyalgia.html
  20. Mij

    Invivyd - monoclonal antibodies

    https://www.invivyd.com/
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