The Role of Psychological Flexibility in Health-Related Quality of Life Among Patients w/[PPS] Associated With Indoor Environment ... 2026 Selinheimo+

[Andy]

Full title: The Role of Psychological Flexibility in Health-Related Quality of Life Among Patients With Persistent Physical Symptoms Associated With Indoor Environment and Chronic Fatigue – 9-Month Follow-Up of a Randomized Controlled Trial

Abstract​

Background​

Persistent physical symptoms (PPS) can significantly impair health-related quality of life (HRQoL). Psychological flexibility (PF), characterized by the ability to adapt functionally and congruently to diverse situations based on personal values, may moderate the impairment of HRQoL. This study examined whether the intervention based on internet-delivered acceptance and commitment therapy (iACT) combined with individual case formulation and treatment as usual (TAU) (n = 50) was effective in improving HRQoL compared to TAU alone (n = 53) in adults with PPS associated with indoor environment and/or chronic fatigue syndrome. Then, the mediating role of PF was explored.

Method​

In this trial (ClinicalTrials.gov NCT04532827), self-report questionnaires were administered to evaluate HRQoL, and PF, including general PF, cognitive fusion, and thought suppression. The primary outcome was HRQoL. Outcomes were assessed at baseline, at post-intervention (3 months from baseline), and at 3- and 9-month follow-ups from post-intervention.

Results​

Significant interaction effects for HRQoL were found in the iACT + TAU group from baseline to the 9-month follow-up (p = 0.003), indicating the HRQoL increased more in the iACT + TAU group, compared to the TAU alone (p = 0.164). PF did not mediate the change of HRQoL during the follow-up.

Conclusion​

The iACT + TAU combined with individual case formulation significantly increased HRQoL compared to TAU alone. However, no mediation effects were observed, suggesting that PF did not mediate the change in HRQoL. Further research on mechanisms of change is warranted to enhance understanding of both conditions and lead to more effective treatments.

Open access

 

[Peter T]

Let’s keep on trying to work out what mediates changing people’s questionnaire response behaviour so we can generate more impressive fake evidence that our interventions actually have any impact on people’s real life.

 

[duncan]

Psychological flexibility (PF), characterized by the ability to adapt functionally and congruently to diverse situations based on personal values, may moderate the impairment of HRQoL.

Personal values??

How is there not a toxic level of judgment already embedded in one of their first (contrived?) definitions? When this protocol fails, what does it say to the patient about his/her personal value system?

 

[rvallee]

The idea behind this seems to be that people living with disabling chronic symptoms should behave the same as people without, and that's just completely ridiculous.

Also a very blatant example of lack of psychological flexibility. They are completely inflexible in holding opinions contrary to all evidence in front of them. This is actually getting deep into fanaticism territory.

When AIs become smart enough to perform actual systematic reviews of this junk, it will light up the "WTF is this shit?!" layers so bright you could grow plants with it, and it might actually decide all on its own to build itself a working arm-and-hand just to smack them behind the head. That's if it doesn't just decide to delete itself.

Actually, suggesting to delete everything is likely to be the strongest recommendation any smart AI will make. There is absolutely nothing to salvage here.