The scientific basis for fatigue, 2025, Martin et al.

M

MinIreland

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Book: The scientific basis of fatigue, 2025, Martin et al.


[Need to edit cause need to figure out how to add tags]

About the book​

Key Features​

  • Reviews molecular and cellular aspects of chronic fatigue syndrome
  • Outlines fatigue in relation to various conditions including diabetes, Parkinson’s disease, and stroke
  • Includes mini dictionary of terms and summary points for each chapter

Description​

Fatigue is a prevalent problem and adequate treatment is challenging because many conditions, disorders, medications, and lifestyle factors can cause fatigue. The Scientific Basis of Fatigue combines evidence-based research and clinical treatment protocols to provide a comprehensive reference to fatigue. This book is divided into seven distinct sections, starting with an introduction section defining the distinctions between physical and mental fatigue. The second and third sections detail the various conditions in both physical and mental fatigue including COVID, Parkinson disease, and depression. The next section reviews the current research on molecular and cellular aspects and models of fatigue. The final two sections review options for diagnosis and treatments for fatigue and provides a detailed resource section for further review.

Link to the book here

Unfortunately, this book is very expensive but I wanted to share it anyway. Not everything is related to ME/CFS. There are also chapters that focus on cancer and COVID-19. I have been able to get my hands on the ME/CFS chapters, but I don't know when/if I'll have the energy to summarize them. If anyone would like to do this, please send me a Direct Message.

I was hoping one of the doctors on this forum would be able to get their hands on the book and filter out what is relevant for us (@Jonathan Edwards ?). I don't know if there is anything new, but it is very recently published, so worth exploring.
 
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Allow me to quote from chapter 7:

"

Therapeutic approach​

Managing CFS typically involves a multidisciplinary approach tailored to each patient’s specific symptoms and needs. Conventional treatments focus on symptom management, such as pain relief, sleep improvement, and psychological support. Cognitive-behavioral therapy (CBT) and graded exercise therapy (GET) have emerged as leading psychological and physical interventions (Bested and Marshall, 2015, Nijs et al., 2012, Sandler and Lloyd, 2020), respectively, showing promise in improving overall functioning and QoL for some patients."

I'm not going to read any further than this.
 
I saw this some weeks ago. I haven't been able to read through but glanced quickly at the PDF of the management chapter (due to Grach, Seltzer et al) - it was very EDS-POTS-MCAS-CCI centric; unfortunately, I don't think it can be relied upon for reasonable advice about management.
 
fresh_air said:
Allow me to quote from chapter 7:

"

Therapeutic approach​

Managing CFS typically involves a multidisciplinary approach tailored to each patient’s specific symptoms and needs. Conventional treatments focus on symptom management, such as pain relief, sleep improvement, and psychological support. Cognitive-behavioral therapy (CBT) and graded exercise therapy (GET) have emerged as leading psychological and physical interventions (Bested and Marshall, 2015, Nijs et al., 2012, Sandler and Lloyd, 2020), respectively, showing promise in improving overall functioning and QoL for some patients."

I'm not going to read any further than this.
Click to expand...
Now that's interesting, because in chapter 45 (Managing ME/CFS: A new narrative) it says:

"Pacing has been demonstrated to be more effective for managing symptoms in ME/CFS patients compared to other interventions such as graded exercise therapy, which has been linked to patient deterioration" (p 538)

Perhaps the editor should have challenged the chapter 7 authors!
 
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