Two coronaviruses isolated from central nervous system tissue of two multiple sclerosis patients

[Mij]

Abstract
Two coronaviruses were isolated from brain material obtained at autopsy from two multiple sclerosis patients. The viruses were neutralized by serum and spinal fluid from these patients. Although most of the population have antibody to these virus isolates, multiple sclerosis patients have slightly higher concentrations of serum antibody than controls. The results suggest that coronaviruses should be considered as one additional virus with a potential implication in the etiology of multiple sclerosis.

https://www.science.org/doi/10.1126/science.7403860

 

[duncan]

Two coronaviruses were isolated from brain material obtained at autopsy from two multiple sclerosis patients...The results suggest that coronaviruses should be considered as one additional virus with a potential implication in the etiology of multiple sclerosis.

Add Covid to the growing list of pathogenic candidates behind MS.

It's such a rare thing to see someone actually testing tissue, and brain tissue at that(!), for any neurological disease.

 

[duncan]

The viruses were neutralized by serum and spinal fluid from these patients.

I can only access the abstract. Not sure what this quote is saying.

 

[hinterland]

I can only access the abstract. Not sure what this quote is saying.

I think it’s suggesting that the serum and CSF contained neutralising antibodies, but haven’t read the paper either.

 

[duncan]

I have a low regard for what they can infer from serum and CSF to begin with.

The viruses were neutralized by serum and spinal fluid from these patients

Out of context, this can mean a few different things. I suppose it hinges - in part - on what they mean by "neutralized".