Taste buds do not contain a resident immune system and TRCs account for all cells within taste buds.
In contrast to SARS-CoV-2 infection in the olfactory system where it is the sustentacular cells that are affected our data show evidence for infection in the taste apparatus per se i.e. the taste buds.
Replication of virus can likely then occur undisturbed and allow for transmission from the taste bud into circulation, and locally infect lingual and salivary gland epithelium, oral mucosa and larynx and even on into the lungs.