Upadacitinib (rinvoq)--could it reduce fatigue in ME/CFS?

[ellesa]

Douglas Fraser also mentioned a potential diagnostic panel and a commercial agreement with Thermo Fisher in the video, which is pretty exciting

 

[ellesa]

I've just posted this grant https://www.s4me.info/threads/niaid-r01-grant-to-study-persistent-lung-injury-in-long-covid.44851/

Over the next five years, the researchers will pinpoint exactly how interferon-gamma from T cells sparks this chronic inflammation, test whether blocking its partner pathway (STAT1) in macrophages prevents long-term damage, and chart the entire molecular chain in search of drug targets.

Sounds like this team may also be studying JAK inhibitors?

 

[Jaybee00]

Three clinical trials for Long COVID are testing JAK inhibitors to treat immune dysregulation​

Three clinical trials for Long COVID are testing JAK inhibitors to treat immune dysregulation - The Sick Times

Three separate trials are testing the immunomodulator drugs abrocitinib (Cibinqo), baricitinib (Olumiant), and upadacitinib (Rinvoq). All are JAK inhibitors, which target specific inflammation pathways.

thesicktimes.org

This article was posted on this forum on a different thread.