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Sorry if I'm not too bright, but the process for checking these would be going to 23andme, going to id02 and just searchign for the snp#s? Because I got no results. I have a WGA whose data I put into promethease and the SNPS didn't come up there either (though it only shows 1 snp on IDO2 which...

I actually came across this on the OMF site, I had never heard of before - basically a nitrogen trap. https://www.omf.ngo/nitrogen-metabolism-and-testing-nitrogen-hypothesis-in-me-cfs/ You can take a look at all their projects about half way down their webpage, there is quite a bit going on...

I'm a little surprised metabolic trap progress has been slow. It's worth noting that OMF recieved a $1M donation specific for the metablic trap hypothesis in mid-2018. They recieved $5M in 2017 due to a bitcoin billionaire. https://www.omf.ngo/pineapple-fund/ And $2M in late 2019...

I just read the transcript from the March 30th call. I have to say I'm disappointed even by me/cfs standards. How can you have a mandate to complete an intramural study for a underfunded, underserved condition and just drop it with ambiguous (read none) plans to return? Don't get me wrong, I'm...

Without being able to read the full article, I believe this is evidence in support of the idea that long-haul is not me/cfs, only a subset of it may be. A good portion of longhaulers are reporting gradual improvement, even up to a year plus. This will produce a divergent narrative as well. In...

Here is a bit of history on the Cavitat on quackwatch: https://quackwatch.org/related/cavitation/ Basically it is an ultrasound device. It's supposed to be superior for detecting jawbone cavitations over an x-ray. I have no idea if it's true or not. The idea of this silent infection causing...

Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel diseas, Bager et al https://pubmed.ncbi.nlm.nih.gov/33210299/ Health Rising had a guest blog feauturing this study...

Interesting, but intimidating drug combo. Both case reports were responders to previous interventions, suggesting some degree of known auto-immunity. Both relapsed after 6-7 weeks.

I can't believe you would accuse Paul "I don't have post-viral illness" Garner of having a shifting narrative.

OBJECTIVES--To determine the symptomatic and functional status during follow up of patients referred to hospital with unexplained fatigue and to identify patient variables associated with persistent functional impairment. DESIGN--Follow up by postal questionnaire six weeks to four years...

I find it strange he left out his deep belief in psychosomatic illness and his own publication from his BMJ blog, given how his psychology scheme left the biggest impact of his undergrad education.

People should read this imo. Amongst the pretentious narrative are a deferential belief in psychosomatic illness, a strong dilineation between the mind and body and claim the pyschotherapy has never hurt anyone along with a discussion of transference and some strange "examples" of psychosomatic...

Is this the same Paul Garner? Psychotherapy: experience as a medical student http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC1504610&blobtype=pdf

But isn't that exactly what the Rowe/Visser paper is trying to do, to suggest OI may occur in patients when BP and HR have normal responses and that this may be due reduce cerebral blood flow? I understand the critcisims but there certainly seems to be a strong presence of OI in me/cfs that is...

Wow. I expected the claim to be overblown, but not amount to a single incident. That incident itself reading like cheap fanfic that at worst isn't even hearsay of death-threat. @strategist https://www.bmj.com/content/340/bmj.c1099, the other propogator of the death threat narrative happened to...

Trying to remember the paper where I first read this, I think it Wessley or White, but it was an older paper that highlighted financial gain (e.g. from disability) as well. edit: So far, couldn't find the paper I was looking for, although this one (1992) by Sharpe. My bolding. Telling...

Based on what I read in, I think it was a New Yorker article on Resignation syndrome, it seems that very few cases, with a specific group of doctors speaking to the media. In many ways it was inconsistent with psychogenic illness but very consistent with creating a narrative. It wasn't clear...

Is that saying exhation 60% do not have exhaustion after exercise/work?

I read your earlier post about the possibility of me/cfs in animals. It is intriguing, but also possible like @Jonathan Edwards says, it might just not happen. If it does, it seems awful hard to validate me/cfs. I'm also not sure how valuable it would be if it did happen and could be dxed...

One lingering question I have about the WSJ article, I read on screenshots. Does the link *prevailing* view just link to the PACE trial or does it link to evidence that it is the prevailining view. Because it would be, frankly incorrect to make a statement about the prevailing view and then...