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Employers’ Long Game for Long Covid Scott Conard, Mark Cunningham-Hill, Mohannad Kusti, , Suresh Mukherji, Wayne Rawlins, Stan Schwartz, and Co-authored by members of the National Alliance of Healthcare Purchaser Coalitions’ Medical Director Advisory Council [Line breaks added] In-Brief The...

This seems like a good resource. I read one guide so far, 'Standard deviation versus standard error'. It's a fairly easy to follow explanation of the consequence of studies accidentally using standard error instead of standard deviation in meta-analyses. And it gives three explicit examples of...

T and B cell responses against Epstein–Barr virus in primary sclerosing cholangitis [Line breaks added] Abstract Primary sclerosing cholangitis (PSC) is an idiopathic, progressive and incurable liver disease. Here, we aimed for systematic analyses of adaptive immune responses in PSC. By...

Nature: 'How to spot suspicious papers: a sleuthing guide for scientists' An open collection of tips and tools could help researchers and publishers to pick up on problematic research. By Miryam Naddaf ---- 'A group of research-integrity experts has launched a toolkit for researchers that...

Copied from COSIG homepage: --------- Anyone can do post-publication peer review. Anyone can be a steward of the scientific literature. Anyone can do forensic metascience. Anyone can sleuth. However, investigating the integrity of the published scientific literature often requires...

Statistics 101 from OMF Science Wednesdays: ---- Statistics is considered a mathematical way to describe data and test hypotheses. Some of the fundamental components of statistics include p-values, regressions, and confidence intervals. What is a...

Using a percentile here somewhat downplays it. On the Qeios page for these stats, it says this paper is ranked number 1 out of 8 for papers of a similar age from Qeios.

The Scientist: 'The “Virus Hunter” Who Advanced Public Health, One Tool at a Time' In his 40-year epidemiology career, Ian Lipkin has done it all: from discovering 2,000 viruses to solving a nationwide SARS crisis. by Shelby Bradford, PhD ---- 'Alongside his pathogen discovery work at the turn...

The Canary: 'A groundbreaking documentary on ME/CFS is now available to international audiences' ---- 'The documentary has gone live to rent on Vimeo. The film is in German, but international viewers can select various subtitle options to follow it in their preferred language. However, if you...

Long-COVID is associated with increased absenteeism from work Jaewhan Kim, Sanghoon Lee, Peter Weir [Line breaks added] Abstract Long-COVID, defined as COVID-19 symptoms persisting for more than 3 months, may lead to persistent health issues requiring extensive medical care. Despite its...

I tried reading the paper, and can't understand most of it. But I think the main idea is this: they're not looking for SNPs that cause these conditions. They're looking for SNPs that cause increased variation in getting the condition (in other words, SNPs that increase the influence of...

Depression Anxiety Autistic traits Psychotic-like experiences

Genetics of monozygotic twins reveals the impact of environmental sensitivity on psychiatric and neurodevelopmental phenotypes Abstract Individual sensitivity to environmental exposures may be genetically influenced. This genotype-by-environment interplay implies differences in phenotypic...

Amplification of select autonomous HERV loci and surrounding host gene transcription in monocytes from patients with post-acute sequelae of COVID-19 Hyunmin Koo, Casey D. Morrow [Line breaks added] Background The human genome contains approximately 3,200 near full-length autonomous human...

The Implications and Predictability of Sleep Reversal for People with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Machine Learning Approach Meghan P. Dietrich, Raam Pravin, Jacob Furst, Leonard A. Jason Background/Objectives: Impaired sleep is one of the core symptoms of myalgic...

I can't find one from a quick search, but maybe an auto-translation of the relevant parts would be okay?

Interestingly, scyllo-inositol has been tested as a treatment for Alzheimer's, bipolar disorder, and down syndrome, with apparently negative results in all. (Wikipedia)

Forensic biomarker discovery: Utilising metabolomics to elucidate prospective fatigue biomarkers for eventual roadside detection Aaron Hamilton, Luke Whiley, Maria Kadyrov, Brendan Chapman Highlights • Metabolomics can be used to identify biomarkers for fatigue. • Scyllo-inositol...

Agree with other posters - very well written and thorough. I wonder if the diagnostic criteria might be a factor. CCC in Fluge et al, but CCC and/or IOM here, so maybe the factor in the blood wasn't necessarily related to ME/CFS, but was related to a comorbidity required by CCC but not by IOM.

Here's an association, but this specifically is only describing healthy controls. It's a positive correlation between Vitality (SF-36) and IGHV3-23/IGHV3-30. r=0.527, q=0.039. The more they have the healthier they are, so opposite direction of the association between controls and ME/CFS in the...