Search results

  1. V.R.T.

    Preprint Initial findings from the DecodeME genome-wide association study of myalgic encephalomyelitis/chronic fatigue syndrome, 2025, DecodeMe Collaboration

    Wow, that's really intriguing.
  2. V.R.T.

    Closed UK: DecodeME updates, was recruitment thread.

    A massive thank you to the whole DecodeME team! I'm very grateful to everyone who made tonight possible. Lets hope its the start of an interesting and fruitful journey!
  3. V.R.T.

    DecodeME in the media

    I really wish they would just give it an effing rest.
  4. V.R.T.

    Criticisms of DecodeME in the media - and responses to the criticisms

    I really wish they would just give it an effing rest.
  5. V.R.T.

    Preprint Initial findings from the DecodeME genome-wide association study of myalgic encephalomyelitis/chronic fatigue syndrome, 2025, DecodeMe Collaboration

    So if the gene inhibits the proliferation of CD4+CD8 t cells activated by IFNG does that provide evidence for or againsts JE et als hypothesis? Inhibition would suggest against to me but I know little about these things.
  6. V.R.T.

    Preprint Initial findings from the DecodeME genome-wide association study of myalgic encephalomyelitis/chronic fatigue syndrome, 2025, DecodeMe Collaboration

    Looks like the top hit gene has never been mentioned on here before...
  7. V.R.T.

    News From Jarred Younger / Neuroinflammation, Pain, and Fatigue Laboratory at UAB, From Aug 2020

    Any statement by researchers which contributes to the phenomena of patients confidently stating unproven hypotheses as fact, further delegitmising them in the eyes of medics, is deeply irresponsible imo.
  8. V.R.T.

    Closed UK: DecodeME updates, was recruitment thread.

    I think the rest of the community would have had a thing or two to say about that...:joy:
  9. V.R.T.

    Closed UK: DecodeME updates, was recruitment thread.

    This is incredibly exciting! Thank you to the whole team! P.s. i picked the wrong week to move house :eek:
  10. V.R.T.

    Teclistamab for ME/CFS

    Agreed. Hopefully if any theraputic experiments follow on from DecodeME they will include controls from the get go.
  11. V.R.T.

    Teclistamab for ME/CFS

    Mella said so in his Charite talk this year.
  12. V.R.T.

    New Swiss study probes lingering fatigue after Legionnaires' disease

    My definite (as opposed to possible prodromal) onset was after a dual strep and impetigo infection. Interestingly not the strain of strep that causes impetigo so two different infections. Point is bacterial infections definitely seem to be a trigger.
  13. V.R.T.

    Metabolic adaptation and fragility in healthy 3-D in vitro skeletal muscle tissues exposed to [CFS] and Long COVID-19 sera, 2025, Mughal+

    The question is have they created PEM in a dish or found the factor that causes ME/CFS exercise intolerance and muscle weakness/fatiguability? As opposed to delayed PEM.
  14. V.R.T.

    Review Causes of symptoms and symptom persistence in long COVID and myalgic encephalomyelitis/chronic fatigue syndrome, 2025, Komaroff et al.

    Precicely i feel like they are talking about something that isnt neuroinflammation. These new drugs they are talking about are intriguing but I don't find it particularly compelling as a hypothesis.
  15. V.R.T.

    Review Causes of symptoms and symptom persistence in long COVID and myalgic encephalomyelitis/chronic fatigue syndrome, 2025, Komaroff et al.

    I don't feel like the authors provide any evidence that neuroinflammation is the cause. And also is the definition that its 'immune activation within the brain' accurate? But the idea of targeting the sickness behavior itself rather than the cause of it is kind of intriguing. I guess time will...
  16. V.R.T.

    Review Causes of symptoms and symptom persistence in long COVID and myalgic encephalomyelitis/chronic fatigue syndrome, 2025, Komaroff et al.

    Does the idea that its caused by neuroinflammation and will need new anti-inflammatory drugs to treat carry weight with anyone round here? It sort of seems like a shrug type response to me...
  17. V.R.T.

    News from the USA, United States of America

    Do we know if the DecodeME team will be attending?
  18. V.R.T.

    What research do you want to see? (study ideas)

    Yeah this work is facinating and if it replicates it could be really important.
  19. V.R.T.

    Metabolic adaptation and fragility in healthy 3-D in vitro skeletal muscle tissues exposed to [CFS] and Long COVID-19 sera, 2025, Mughal+

    What are the implications if this study replicates? If the factor in the serum causing these responses can be identified and removed, will cells and muscles return to normal? The paper calls these effects transient, so one would hope so... And would this finding gel or clash with the...
  20. V.R.T.

    Metabolic adaptation and fragility in healthy 3-D in vitro skeletal muscle tissues exposed to [CFS] and Long COVID-19 sera, 2025, Mughal+

    What was the sample size here, out of curiosity?
Back
Top Bottom