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I don't know, to be honest. How would I be able to tell? I suspect that I have difficulty making enough serotonin because I do well on 5-HTP (for depression) which increases serotonin levels. I've been on 5-HTP for years, and was taking it when I first tried amitriptyline. I have never taken a...

Amitriptyline does reduce pain for me, but it also gives me tachycardia, so I can't take it. Since tachycardia is a known side effect mentioned on the Patient Information Leaflet I'm wondering if the connection between the Amitriptyline and tachycardia is understood. It strikes me that it could...

I think Michael Sharpe would probably prefer to leave the country rather than take part in any form of debate.

So, why don't doctors treat this in the short term with potassium supplements, and give the patient dietary advice on which foods they can eat to raise their potassium levels and prevent the problem from happening in the first place? Or is this condition more complicated that it appears on the...

Exogenous T3 stops affecting blood test results of Total or Free T3 within about 24 hours. T4 (Total or Free) can affect test results for much longer - a week or so, but by the end of that time the levels in blood which originated from any exogenous treatment would be very low indeed. If the...

If you read this whole Twitter thread it turns out that IAPT is working out roughly how you might expect it to i.e. extremely badly!

I really wish I had your optimism. Edit : Sorry that sounds nasty, and it wasn't my intention. I'm simply not an optimist when it comes to anything medical.

Apparently it was. https://en.wikipedia.org/wiki/It%27s_a_Good_Life_(The_Twilight_Zone)#Cast

If CBT is the "answer" for cases of IBS does that mean that we can expect colon cancer to become far more prominent in the "causes of death" statistics in future? And what about diverticular disease leading to perforations, followed by sepsis that then leads to death?

"It's A Good Life" by Jerome Bixby. The original short story was written in 1953 and it has been anthologised, I would guess, dozens of times.

I thought this article would be of interest since the problem being discussed caused long-lasting post-viral fatigue. I was surprised by the diagnosis - it was something that I've never come across personally, although I have heard of it. Link ...

Just read the first paragraph I was under the impression that increases in life expectancy had not just stalled but had gone into reverse, and this started around 2012.

I wonder if anyone else thinks the government is trying to drive GPs away from primary care medicine in the UK. I'm not sure what they want to replace them with, but I am certain it will involve the private sector, and substantial costs to the public.

For what this is worth (anecdotal, so of little value), I have read posts by someone on another website whose TN went into remission with (I think) methylcobalamin and methylfolate. There are four different kinds of vitamin B12 available and I think they found that they had to try several kinds...

Another article (from the BBC this time) on the effects of using mesh : Life after vaginal mesh surgery

You might find the two links in this post help to answer your question : https://www.s4me.info/threads/unintended-consequence-of-poorly-thought-out-legislation-not-important.8904/#post-157171 Certain drugs, usually those which are addictive, have rules attached about who can prescribe, how...

Thanks for the hansard link. I'm glad there are some people in parliament with a heart. I still think there are plenty of politicians who had theirs excised at some point in their lives, but that could just be my own prejudice.

'We're absolutely appalled' say mesh campaigners over NICE decision I'm absolutely appalled too. This is NICE telling women everywhere to piss off because their experiences and their quality of life is of no interest and of no importance to the NHS. Saying there is "limited evidence on the...

Do you have some evidence for this? I am not trying to be combative. I just haven't seen any evidence for separate vaccines being worse than combined ones, nor can I see how this can be true from a logical point of view. Challenging and stressing the immune system, particularly of very young...

One of the things that worries me about vaccines is that nowadays they are given from birth onwards. I wonder what effect this has on immature immune systems. And since most of the vaccines/immunisations are not that old, nobody knows what effects they may have in a few decades time. The...