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I think they are saying where there are things with potential symptom overlap then they are excluding. I don't think that is good they should at least consider the order of symptoms/different illnesses etc. T The IoM guidelines were much more careful not to exclude for the sake of it and I seem...

Some are. Many are concerned about careers and end up following the fashion in research, I suspect in part as that is where the money is. Some who aren't very good at science seem to take up positions in academic or research management and have way too much influence. Many if not most go into...

There was a 2.5 year follow up for PACE which Sharpe spun as supporting PACE (because improvements remained) but the other arms caught up. Looking at the TSC/TMG minutes a major part of the follow up should have been economic data but this was never published. In addition there were plans that...

(Edited by moderator to reduce confusion that might arise resulting from deletion of other posts.) As a general piece of advice if you are concerned about a link it can be worth running it through virus total first before going there https://www.virustotal.com/#/home/url They run the link...

Looks like a false alarm that they have corrected. https://reports.adguard.com/en/me-quiz.epizy.com/report.html Moderator note: A number of posts have been deleted from this thread related to the safety of the linked website. The website has been found by forum admin to not present a phishing...

I think its more due to their beliefs and failures of logical reasoning in terms of their inference 'don't understand => psychosomatic' . Which is precisely the inference that seems to be the basis of this article. But I don't think they actually provide any argument to backup their claim just...

I would have thought that epidemiology should be really interesting. But maybe I've misunderstood what it is. Now we have large amounts of data and ways to process and learn patterns then looking at disease spread patterns should be a reinvigorated. I think google can predict an outbreak of the...

I've been thinking about some of Sharpe's comments and they only seem to make sense if he really believes that ME is caused by disfunctional beliefs thus that is how he defines it. But even if this were the case his trial design is only robust iff a change in these beliefs is the only factor...

I remember thinking at the time that this was coordinated with White and his submission

But only if they have the ability to influence the trial. Giving money to a cause is not a CoI. A cause taking money from someone with alternative interests could be. My point about QMUL is that as an organisation (and legal entity) they were highly involved in the trial (as primary sponsors...

Effective communication often involves understanding the audience. So we need different styles to interact/influence/catch the attention of different groups. But we also need to understand that this is not just about communication but its an adversarial situation where there are groups with...

I assume there is also a concept of past reward implying future reward. So if I have done work for insurance companies in the past then I am likely to do so in the future assuming good status follows from good results. The thing I am wondering about whether institutions should declare CoIs...

I think you are getting confused with people giving medical advice to insurance companies and people with actual management positions. No company in their right mind would appoint Sharpe as a CEO as he has no management experience and if they did their share price would plummet (the markets care...

I think the PACE people had tried to push the message that the reanalysis didn't show anything different from their published results (I guess they would claim a statistical significance) so it may be pandering to that view.

I think this exposes other issues with SF36 as a scale. Really to be a scale there should be an expected order and linearity of response but if people find (and judge severity) different activities have different difficulties then its not really ever going to be a scale. There is no expected...

I wasn't intending that rather to echo what I thought a therapist may say to convince you that your levels of activity are normal and hence change your scores. If we know we our own judgement on these things are contextual and difficult then we cannot trust subjective assessments

I think you are right in terms of publications. But I think there is good research going on and it does take time to do it and publish.

But Graham as you get older everyone has problems with walking what your experiencing is just normal - don't you want to get better? If I got a CBT therapist to repeat this to you in sessions over a year would you change your view of what is difficult and change the box you tick? If you did I...

Sometimes people with absolute certainty do very well. Until they run across people who know they are wrong or their certainty contradicts their usefulness.

I assume it becomes an issue for many patient charities with magazines that many of the companies who wish to advertise will be selling alternative medicine, unproven supplements etc. One of the reasons for not taking advertising here. It could get worse with websites where advertising is...