Search results

The so called worried well are a convenient scapegoat on which to blame the financial difficulties of the NHS. I wonder if it's a coincidence that the author is a psychologist. In the UK at least, the profession seems to have been happy to promote an anti-patient agenda.

This is of interest because the patient reportedly improved substantially after moving into a cleaner home environment. We keep hearing stories like this one. There is also a bit about SNPs of the patient GSTT1 (Primary Glutathione biosynthesis): Null/Absent GSTP1 A/G SOD2 (Superoxide...

Environmental Exposures as a Potential Underlying Factor in Chronic Fatigue Syndrome; a Case Report An Environmental Medicine perspective on a complex syndrome; Could toxic exposures be the cause? http://www.journals.ke-i.org/index.php/mra/article/view/1573/1626

Yes, often. Sometimes it seems that the problem starts in the gut and then expands.

Sounds like the patients with worse memory are also *gasp*, who would have thought, sicker in other areas. As in, think of a time you were healthier, and now do your GET? I also like how they went from a correlation (assuming it's even true) to causality.

ME/CFS could become a hot field in research. The illness is probably poorly understood because it's different than other illnesses. As soon as there are signs that progress can be made, to researchers it will no longer look like an unsolvable frustrating problem but an exciting opportunity.We...

Excellent letter. May I suggest clearly saying that this is an opportunity for NICE to resolve some of the controversy surrounding ME/CFS.

@Jonathan Edwards Ron is now saying that the metabolic signature in ME/CFS has some resemblance to diabetes. I've been saying for a while that problems with blood sugar regulation seem to be common among patients. This could be low hanging fruit for a researcher. If I'm right then a 4-5 hour...

I think all of these Writing that PACE is junk science in the JHP special issue. I'm pretty sure the JHP special issue will be considered. It should be at least. Advisor to IiME would probably exclude someone. Anyway, this sounds like a very good development. NICE may have finally...

You recently said that pathogens have not been excluded as cause of ME/CFS. My question is: what kind of pathogens do you think might be involved, and where in the body do you think the infection is, and what kind of research needs to be done to actually fill this knowledge gap?

Sounds worsen that British psychobabble. Germany is really backwards it seems.

This is how lower respiratory capacity, mentioned in the article, was interpreted in a previous study: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0186802

The Trump administration is weird. Wonder how long it will take before Trump is removed from his post due to lack of ability to properly carry out his duties. Or maybe there is some strategy behind this, a desperate attempt to create controversy in order to distract from real problems, such as...

We have had good discussions about the Chalder Fatigue Scale before. Now is the perfect time to explain why it's a bad instrument. In general an important task would be to make sure that instruments and definitions based on poor science don't influence the common data elements.

It's open now. This is VERY important stuff! This is about trying to come up with good standard for defining and measuring key symptoms and various aspects of ME/CFS. https://www.commondataelements.ninds.nih.gov/MECFS.aspx#tab=Data_Standards Please be respectful if some definition is poor...

Was a reason for the rejection given?

I liked it, but expected more participation. The announcement thread seemed to generate more unique users with questions than the actual event. Not sure why that is. Perhaps timezone differences. That could be worked around by collecting some questions beforehand from users who won't be able to...

How many applications from researchers requesting samples is the biobank getting? Is interest in ME/CFS increasing?

Of course GPs are stressed out. The NHS is collapsing due being starved of funding. The policy of treating complex or unexplained illness as psychosomatic, promoted by Gerada, Wessely, etc is a good way to poison doctor patient relationships. A little more humility would be easier for everyone.

Basically what they are saying is that it's not possible to compare a genetic defect of pyruvate dehydrogenase (PDH) with suppression of PDH (technically, increased expression of inhibitory pyruvate dehydrogenase kinases). Also that the abnormalities observed in patients are difficult to explain...