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  1. Sasha

    "Exercise in a pill" - potential for ME/CFS?

    The mention GW1516, irisin, Compound 14, and cathepsin b, but I can't see Sestrin.
  2. Sasha

    "Exercise in a pill" - potential for ME/CFS?

    I'm looking at the print edition and it doesn't provide references.
  3. Sasha

    "Exercise in a pill" - potential for ME/CFS?

    It's in the 24 April edition, pp. 46-49. Tagging @Simon M, in case you're interested!
  4. Sasha

    "Exercise in a pill" - potential for ME/CFS?

    The article talks about a variety of drugs (I shouldn't have posted this when I'm so tired and can't summarise - so sorry!). I think it's a massive concern for PwME because so many of us can barely move and are going into old age having had zero exercise, for decades. There's lots of research...
  5. Sasha

    "Exercise in a pill" - potential for ME/CFS?

    In the longer article, there was rather more to it than that (apologies again, I'm too tired to summarise, which must be very frustrating for everybody!).
  6. Sasha

    "Exercise in a pill" - potential for ME/CFS?

    The pill doesn't enable you to exercise more - it enables you to have the physiological benefits of exercise without moving. Hence my interest! :)
  7. Sasha

    "Exercise in a pill" - potential for ME/CFS?

    This (mostly paywalled) New Scientist article says: I've read the whole article and it's interesting. I'm very sorry but I'm too tired to summarise it properly! But basically, scientists have used drugs on mice that give them the health benefits of exercise. There are concerns about impacts on...
  8. Sasha

    DecodeME - UK ME/CFS DNA study underway

    When is ME Awareness Day, @Andy? Does this push deserve its own thread and a place on the banner?
  9. Sasha

    DecodeME - UK ME/CFS DNA study underway

    @Trish, Thanks for those notes, very helpful! Quick question: is that 'age over 16' or should it be '16 and over'?
  10. Sasha

    ME Association Statement on Exercise in ME/CFS and Long Covid, April 2021

    The MEA have always said 'one size doesn't fit all' in relation to GET, as though the issue was with not individualising the treatment. I really wish they'd drop that attitude. As you say, there's zero evidence that that's the issue, and plenty that it isn't.
  11. Sasha

    Book in Sweden by professor emeritus Kjell Asplund on research misconduct and narcissism

    It has surprised me, in the context of PACE, that in the UK at least, 'research misconduct' doesn't seem to be a 'thing' - at least, not in the sense of a crime or misdemeanour that you can be found guilty of by some sort of official panel. I wish it was.
  12. Sasha

    George Monbiot on ME/CFS, PACE, BPS and Long Covid

    That looks like poor advice, to be honest - specifically the bit parroting CG53. It's too weak a warning to be much use.
  13. Sasha

    George Monbiot on ME/CFS, PACE, BPS and Long Covid

    A friend of mine just sent me a link to the article knowing I'd be interested, and said that a friend of hers diagnosed with ME/CFS post-Covid has been prescribed GET. How can we stop this unfolding disaster for post-Covid patients?
  14. Sasha

    George Monbiot on ME/CFS, PACE, BPS and Long Covid

    It seems like a major piece of news. I don't recall Sharpe being called out before in the mainstream media for his behaviour like this.
  15. Sasha

    Covid-19 vaccination experiences

    Do many seriously deteroriate?
  16. Sasha

    Preprint: Recovered not restored: Long-term health consequences after mild COVID-19 in non-hospitalized patients, 2021, Augustin et al

    That's a terrible title. I hope this idea that recovery isn't the same as restoration isn't going to gain traction. This is the rubbish that the PACE authors tried to pull, that allowed them to claim that patients had recovered when they hadn't.
  17. Sasha

    Covid-19 vaccines and vaccinations

    But that is my question! Do the vaccines protect against getting Long Covid. I don't think so. We don't have one for ME/CFS and yet we have a symptom-based diagnosis.
  18. Sasha

    Covid-19 vaccines and vaccinations

    Thanks - but I'm specifically interested on whether the vaccine is preventing cases of Long Covid from developing in the first place, as opposed to affecting existing cases.
  19. Sasha

    Covid-19 vaccines and vaccinations

    Is there any data on the extent to which the vaccines prevent or reduce the severity of new cases of Long Covid? (That is, I'm not asking about their effects on existing Long Covid).
  20. Sasha

    Trial in progress: HElping Alleviate the Longer-term Consequences of COVID-19 (HEAL-COVID)

    Would there be any mileage in S4ME and our charities writing to researchers in this area to try to avoid the many ME-blind stupidities coming down the pike? @Andy - anything like this under way?
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